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In this podcast, Dr. Patrick Niaudet, Head of Pediatric Nephrology Department, Professor of Pediatrics, Hopital Necker-Enfants Malades, a current editor for Pediatric Nephrology of "UpToDate", and a participating Editor of "Pediatric Nephrology", 2009, together with Dr. Amira Al-Uzri, Medical Director of the Pediatric Kidney Transplant Program, Associate Professor of Pediatrics, Oregon Health and Science University, discuss the topic of recurrent focal segmental glomerulosclerosis (FSGS) post kidney transplantation in children. Dr. Niaudet gives a thorough overview of the incidence and risk factors associated with recurrent FSGS post kidney transplantation, the genetic abnormalities present in a subset of patients, and potential new treatment options.