Concurrent Session 42:
Lymphocyte Activation III

Chairs: Rene Duquesnoy and Ashwani Khanna

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4:30 #1021 Anti-CD4 antibody attenuates interleukin-2 receptor signaling.
Young Investigator Award

J Goebel, K Forrest, A Franks, F Emmrich, J Mikovits, F Robey, HD Volk and RP Lowry, Mobile, AL; Lexington, KY; Frederick; Bethesda, MD and Berlin, Germany

4:40 #1022 Analysis of the CD40 and CD28 T cell costimulatory pathways in allograft rejection mediated by CD4 and CD8 T cell subsets.
Young Investigator Award

AW Bingaman, J Ha, SR Waitze, C Tucker-Burden, TC Pearson and CP Larsen, Atlanta, GA

4:50 #1023 Signaling via stimulatory a subunit of G-proteins underlines the protective effects of concanavalin A in failing rat hearts after transplantation.

ZT Tan, S Chien and EL Hoover, Buffalo, NY and Louisville, KY

5:00 #1024 Two different pathways to block chronic rejection in an animal transplant model.

M Richter, H Richter, R Grabs and F-W Mohr, Leipzig, Germany and Frankfort, Germany

5:10 #1025 Th1->Th2 immune deviation facilitates, but does not carse tolerance.

XX Zheng, K Kawamoto, Y Li, XC Li, Y Tian and TB Strom, Boston, MA

5:20 #1026 Activated T cell apoptosis induced by hepatocytes and liver non-parenchymal cell is caspase dependent.

Y-J Chiang, L Lu, Y-C Lee, Z Wang, W Li, JJ Fung and S Qian, Pittsburgh, PA

5:30 #1027 Cyclosporine A suppresses the tolerogenic effect of donor bone marrow cells by inhibiting TGF-^b1-mediated apoptosis.

CK Asiedu, W Wang and JM Thomas, Birmingham, AL

5:40 #1028 Immunotoxin FN18-CRM9 is superior to the unconjugated monoclonal antibody (FN18) in inducing protein tyrosine phosphorylation and CD3 internalization.

MM Hamawy, M Tsuchida, ER Manthei, JH Fechner and SJ Knechtle, Madison, WI

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