Grant Recipients

2010
2010 AST Basic Science Faculty Development Grant Todd Brennan, MD
Duke University Medical Center
Research Title: The Innate Immune System in the Regulation of Allospecific T Lymphocytes
2010 AST/Astellas Basic Science Fellowship Grant

Leonardo Riella, MD
Brigham & Women's Hospital/Harvard Medical School
Research Title: Novel Role of the Notch Pathway in Transplantation

2010 AST/Astellas Clinical Science Fellowship Grant Ben Sprangers, MD
Columbia University
Research Title: Study of the immunological mechanisms involved in transplantation tolerance after combined kidney/bone marrow transplantation (CKBMT)
2010 AST/Genentech Branch Out Grant Daniel Goldstein, MD
Yale University
Research Title: Nanoparticles: A novel approach to inhibit the innate immune system after transplantation
2010 AST/BMS Basic Science Fellowship Grant Joseph Scalea, MD
Harvard University/TBRC
Research Title: The Balance of T-Regulatory Cells and Alloreactive T-Cells in the Maintenance vs. Loss of Tolerance
2010 AST/Pfizer Basic Science Fellowship Grant Sarah Bruneau, PhD
Children's Hospital Boston
Research Title: DEPTOR: A novel protein regulating mTOR/Akt signaling in alloimmunity
2010 AST/Pfizer Basic Science Fellowship Grant Esme Dijke, PhD
University of Alberta
Research Title: To B or not to B? - The fate of B-cell memory in B-cell tolerance after ABO-incompatible heart transplantation in infants
2010 AST/Pfizer Basic Science Fellowship Grant Wing-Hong Kwan, PhD
Mount Sinai School of Medicine
Research Title: C5a/C5aR Modulation of Regulatory T Cells in Transplantation
2009
2009 AST/Astellas Allied Health Professionals Faculty Grant Nataliya Zelikovsky, PhD
The Children’s Hospital of Philadelphia
Research Title: Psychosocial Predictors of Non-Adherence Among Adolescent Transplant Recipients: Developing a Targeted Intervention to Improve Adherence
2009 AST/Astellas Basic Science Faculty Development Grant Beek Yoke Chin, PhD
Beth Israel Deaconess Medical Center
Research Title: Carbon Monoxide Promotes Cardiac Graft Tolerance; Role of the Macrophage
2009 AST/Wyeth Basic Science Faculty Development Grant Rebecca Shilling, MD
University of Chicago
Research Title: Mechanisms of T Cell Mediated Chronic Rejection in the Lung
2009 AST/Wyeth Clinical Science Faculty Development Grant Vibha Lama MD, MS
University of Michigan Health System
Research Title: Mesenchymal Stem Cells as Biomarkers and Biomodulator of Chronic Allograft Rejection in Human Lung Transplant
2009 AST/Astellas Clinical Science Faculty Development Grant Laurie Snyder, MD
Duke University
Research Title: Immune Activation and Regulation in Lung Transplant Rejection
2009 AST/Roche Basic Science Fellowship Grant Olaf Boenisch, MD
Brigham & Women’s Hospital
Research Title: Role of the TIM-3: Galectin-9 Pathway in Allograft Rejection and Tolerance
2009 AST/Roche Basic Science Fellowship Grant Antonino Castellaneta, MD, PhD
University of Pittsburgh
Research Title: NOD2 Signaling and Regulation of Liver Dendritic Cell Tolergenicity
2009 AST/Wyeth Basic Science Fellowship Grant Peter Jindra, PhD
Brigham & Women’s Hospital
Research Title: Induction of Transplantation Tolerance by Retroviral Delivery of Alloantigen on Autologous T Cells
2009 AST/Roche Basic Science Fellowship Grant Nalu Navarro-Alvarez, MD, PhD
Massachusetts General Hospital
Research Title: Role of CD47-SIRP Signaling in Hepatocyte Xenograft Rejection
2009 AST/Roche Clinical Science Fellowship Grant Anita Mehrotra, MD
Mount Sinai Hospital
Research Title: Impact of Erythropoietin Therapy on the Alloimmune Response in Kidney Transplant Recipients
* Formerly known as Fujisawa
2008
2008 AST/ASN John Merrill Transplant Scholar Grant Arjang Djamali, MD
University of Wisconsin – Madison
Research Title: Nox and Kidney Allograft Interstitial Fibrosis
2008 AST/CHEST Foundation Clinical Research Grant in Lung Transplantation Sharon Chen, MD, MS
Stanford University School of Medicine
Research Title: “Anti-Viral Treatment Strategy for Cytomegalovirus (CMV) Infections in Lung Transplant Patients Based on DMV-Specific T-cell Immune Responses”
2008 AST/Astellas Basic Science Faculty Development Grant Andrew Cameron, MD, PhD
The Johns Hopkins School of Medicine
Research Title: Prevention of Recurrent Hepatitis C after Liver Transplant using RNA interference
2008 AST/Roche Basic Science Faculty Development Grant Jun Yang, MD, PhD
Children's Hospital Boston
Research Title: Donor Vascular Endothelial PDL1-Mediated Regulation of Transplant Vasculopathy: Mechanisms and Therapeutic Utility
2008 AST/Isotechnica Basic Science Faculty Development Grant Koichi Shimizu, MD, PhD
Brigham and Women's Hospital, Harvard Medical School
Research Title: B Cell-Associated Mechanisms of Transplant Arteriosclerosis
2008 AST/Wyeth Basic Science Faculty Development Grant Mark Rigby, MD, PhD
Emory University School of Medicine
Research Title: Defining the Role of Autoreactive T Cells in Islet Allograft Rejection
2008 AST/Roche Basic Science Fellowship Grant Tina Sumpter, MS, PhD
University of Pittsburgh
Research Title: Molecular Regulation of Tolerogenic Dendritic Cell Function in the Liver
2008 AST/Wyeth Basic Science Fellowship Grant Joshua Mollov, MD
Massachusetts General Hospital
Research Title: Unraveling the mechanism of peripheral T cell tolerance through induction of mixed chimerism
2008 AST/Astellas Basic Science Fellowship Grant Alexander H.K. Kroemer, MD
Beth Israel Deaconess Medical Center, Harvard Medical School
Research Title: Role of NK cells in Transplant Tolerance
2008 AST/Roche Basic Science Fellowship Grant Haofeng Ji, MD
David Geffen School of Medicine at UCLA
Research Title: Regulation of host sensitization by PD-1 (CD279) negative costimulation pathways in transplant recipients
2008 AST/Astellas Basic Science Fellowship Grant Francesca D'Addio, MD
Children's Hospital
Research Title: Role of the novel T-Bet gene in Transplantation Tolerance
2008 AST/Roche Clinical Science Faculty Development Grant Pratima Sharma, MBBS, MSc (CRSDA)
University of Michigan Health System
Research Title: Re-weighting of the Model for End-Stage Liver Disease (MELD): Effects on survival benefit and the burden of renal disease after liver transplantation
2008 AST/Wyeth Clinical Science Faculty Development Grant Isabel Neuringer, MD
University of North Carolina at Chapel Hill
Research Title: Mannose Binding Lectin in Iscehmia Reperfusion and Rejection after Lung Transplantation
2008 AST/Astellas Clinical Science Faculty Development Grant Robert Venick, MD
University of California Los Angeles
Research Title: Relationship of Drug-related Gene Polymorphisms to Pediatric Post-Transplant De-Novo Autoimmune Hepatitis
2008 AST/Roche Clinical Science Faculty Development Grant Lara Danziger-Isakov, MD, MPH
Cleveland Clinic Lerner College of Medicine at CWRU
Research Title: Betaherpesviruses in Pediatric Solid Organ Transplantation: A Prospective Longitudinal Evaluation
2008 AST/Astellas Clinical Science Fellowship Grant Deidre Sawinski, MD
Mount Sinai School of Medicine
Research Title: Panel of Reactive T cell assay in Transplant Risk Assessment
2008 AST/Wyeth Clinical Science Fellowship Grant Allison Webber, MD
New York Presbyterian Hospital - Weill Cornell Medical Center
Research Title: Biomarkers for Safe Minimization of Immunosuppression in Renal Allograft Recipients
2008
AST/Roche Clinical Science Fellowship Grant Jennifer Jackson, MD
Emory University
Research Title: Development of Non-Invasive Monitoring Tools in Pediatric Renal Transplantation
2008 AST/Roche Clinical Science Fellowship Grant Sanjeev Akkina, MD
University of Minnesota
Research Title: Proteomic Analysis for Biomarkers of Interstitial Fibrosis/Tubular Atrophy in Kidney Transplant Recipients
2008 AST/JDRF Fellowship Grant Andrea Vergani, MD
Children's Hospital
Research Title: B cell depletion in diabetes and islet transplantation in NOD mice
2007
2007 AST/Wyeth Clinical Science Faculty Development Grant Pavan Reddy, MD
Institution:  University of Michigan
Research Topic:  The Effect of Lymphopenia Induced Proliferation of donor T cells on GVH Responses
2007 AST/Astellas Basic Science Faculty Development Grant Shivaprakash Gangappa, PhD
Institution:  Emory University School of Medicine
Research Topic:  Immune mechanisms of latent infection-mediated resistance to transplantation tolerance
2007 AST/Wyeth Clinical Science Fellowship Grant

Giovanna Andreola, MD
Institution:  Massachusetts General Hospital
Sponsor:  Megan Sykes, MD
Research Topic:  Understanding the mechanisms of long-term kidney tolerance through the induction of mixed chimerism

2007 AST/Roche Clinical Science Fellowship Grant

Jesse Qian, MD
Institution:  University of California San Francisco
Sponsor:  Flavio Vincenti, MD
Research Topic:  Recovery of Native Kidney Function From Hepatorenal Syndrome After Combined Kidney-Liver Transplant

2007 AST/Astellas Basic Science Fellowship Grant Tsutomu Hirohashi, MD
Institution:  Massachusetts General Hospital
Sponsor:  Joren Madsen, MD, DPhil
Research Topic:  Interaction between NK Cells and Tregs in Cardiac Allograft Vasculopathy
2007 AST/Astellas Basic Science Fellowship Grant Qiquan Sun, MD, PhD
Institution:  The Ohio State University
Sponsor:  Gregg Hadley, PhD
Research Topic:  Blockade of CD103 as a means to prevent tubular injury following allogeneic renal transplantation
2007 AST/Wyeth Basic Science Fellowship Grant Olga Zhdanova, MD
Institution:  New York University School of Medicine
Sponsor:  Edward Skolnik, MD
Research Topic:  Regulation of the Calcium Activated Potassium Channel, KCa3.1, by histidine phosphorylation: A potentially new therapeutic target to inhibit transplant rejection
2007 AST/Wyeth Basic Science Fellowship Grant Samiksha Bansal, MBBS, MS, MD
Institution:  Cleveland Clinic Foundation
Sponsor:  John Fung, MD, PhD
Research Topic:  Characterization of human hepatic stellate cells and their immunoregulatory role
2007 AST Branch Out Grant Olivia M. Martinez, PhD
Institution:  Stanford University School of Medicine
Research Topic:  Innate Immunity and the Differentiation of Neural Stem/Progenitor Cell Allografts
2007 AST/Astellas Clinical Science Faculty Development Grant Paolo Salvalaggio, MD, PhD
Institution:  Saint Louis University
Research Topic:  The cost effectiveness of liver transplantation in the MELD era
2007 AST/Wyeth Basic Science Faculty Development Grant William Steinbach, MD
Institution:  Duke University
Research Topic:  Calcineurin Inhibition to Prevent and Treat Invasive Aspergillosis
2007 AST/Roche Basic Science Faculty Development Grant

Yijin Li, PhD
Institution:  University of Chicago
Research Topic:  Regulation of Alloreactive B cells

2007 AST/JDRF Grant Paolo Fiorina, MD, PhD
Children’s Hospital Boston
Research Topic: Targeting the CXCR4-SDF Axis to Mobilize Autologous Hematopoietic Stem Cells in Islet Transplantation: Reshaping or Vetoing the Immune System
2007 AST/ESOT Exchange Grant Burcin Ekser, MD
Institution: Thomas E. Starzl Transplantation Institute, University of Pittsburgh Medical Center
Sponsor: David K. C. Cooper, MD, PhD, FRCS
Research Topic: Proposed Studies to Investigate Pig Liver Xenotransplantation as a ‘Bridge’ to Allotransplantation: Studies in Baboon Liver Transplantation Models
2007 AST/ASN John Merrill Transplant Scholar Grant Reza Abdi, MD
Harvard Medical School, Brigham & Women’s Hospital
Research Topic: The Novel Role of Beta3 Integrin in Allograft Rejection
2007 AST/ASN John Merrill Transplant Scholar Grant Jonathan Maltzman, MD, PhD
University of Pennsylvania
Research Topic: Role of Adaptor Protein in Regulatory T Cell Proximal Signaling
2006
2006 AST/Roche Clinical Science Fellowship Grant Adam Charles Schaffer, MD
New York Presbyterian Hospital – Cornell
Research Topic: Foxp3 Profiles as Predictors of Renal Transplantation Outcomes
Nominator: Manikkam Suthanthiran, MD
2006 AST/Astellas Basic Science Fellowship Grant Heth Roderick Turnquist, PhD
University of Pittsburgh
Research Topic: Inhibition of Chronic Rejection Through Immune Modulation by Recipient-Derived Rapamycin-Conditioned Myeloid DCs
Nominator: Angus Thomson, PhD, DSc
2006 AST Policy Fellowship Grant Paula Stirnemann, MPH
Saint Louis University
Research Topic: The Cost-effectiveness of Solid Organ Donation and Transplantation
Nominator: Mark Schnitzler, PhD
2006 AST/Astellas Basic Physician Scientist Training Grant Phillip Horne, BS
The Ohio State University Medical Center
Research Topic: CD4-independent, CD8+ T Cell Mediated Alloimmunity Studied Through a Hepatocellular Allograft Model
Nominator: Ginny Bumgardner, MD, PhD
2006 AST/Astellas Clinical Science Faculty Development Grant Dorry Segev , MD
John Hopkins Medical Institution
Research Topic: This research demonstrates mathematical technology for optimization that would greatly expand the benefits derived from Kidney Paired Donations by identifying the best matches possible.
2006 AST/Wyeth Basic Science Faculty Development Grant Mohammed Javeed Ansari, MBBS, MRCP
Brigham and Women's Hospital
Research Topic: Contribution of MHC Class II Molecules on Dendritic Cells in Pathways of Allorecognition and Tolerance
2006 AST/Roche Basic Science Faculty Development Grant Chaorui Tian, MD, PhD
Brigham and Women's Hospital
Research Topic: The major goal of this proposal is to determine whether molecular chimerism can be used to overcome authoimmunity in recurrence of T1D following islet transplantation. The overall approach is to express a MHC class II ß chain from protective haplotypes in bone marrow derived cells of NOD mice.
2006 AST/Astellas Branch Out Faculty Grant Anita Chong, PhD
University of Chicago
Research Topic: Impact of Oral Infection with Listeria Monocytogenes on Allograft Tolerance
2006 AST/JDRF Grant Juliet Emamaullee, PhD
University of Alberta, Canada
Research Topic: Type I Diabetes and Islet Transplantation
Nominator: A. M. James Shapiro, MD, PhD
2006 AST/ATS Research Grant Stavros Garantziotis, MD
Duke University Medical Center
Research Topic: Role of pulmonary innate immunity in the development of alloimmune lung injury after transplantation
2006 AST/ALF Liver Scholar Research Grant Holger Willenbring, MD
University of California San Francisco
Research Topic : Development of in vivo cell fusion into a therapy for a wide range of genetic liver diseases
2006 AST/ASN John Merrill Transplant Scholar Grant Geetha Chalasani, MD
Yale University School of Medicine
Research Topic: B Cell Help for Alloreactive T Cell Memory
2006 AST/ASBMT Clinical Research Grant Fabienne Haspot, PhD
Massachusetts General Hospital
Research Topic: Mechanisms of CD8 Tolerance and Rejection of BMT
2006 AST/CHEST Foundation Clinical Research Grant Vibha N. Lama, MBBS
University of Michigan
Research Topic: Role of Mesenchymal Stem Cells in Lung Transplantation
2005
2005 AST/ASN John Merrill Transplant Research Scholar Grant Soumitro Pal, PhD
2005 AST/CHEST Foundation Clinical Research Grant in Lung Transplantation Laurie D. Snyder, MD
2005 AST/Astellas* Fellowship Grant Mandy Ford, Ph.D.
2005 AST/Astellas* Basic Science Fellowship Grant Iris Lee, M.D.
2005 AST/Roche Fellowship Grant Bridget L. Colvin, Ph.D.
2005 AST/Wyeth Fellowship Grant Ryan Courtney Fields, M.D.
2005 AST/Roche Faculty Development Grant Daniel Robert Goldstein, M.D.
2005 AST/Astellas* Faculty Grant Yuan Zhai, Ph.D.
2005 AST/JDRF Fellowship Grant Adam Griesemer, M.D.
2005 AST International Research Fellowship Grant Satish Nadig, M.D.
2005 AST/Astellas* Basic Scientist Career Development Faculty Grant Jessamyn Bagley, Ph.D.
2005 AST/Schering Plough Women & Minority Career Development Faculty Grant Lisa Michelle Forman, M.D., M.S.C.E.
2005 AST RO1 Bridge Grant Anna Valujskikh, Ph.D.
2005 AST/ESOT Fellowship Grant Paulo Ney Aguiar Martins, MD, PhD
2004
2004 Wyeth/AST Council's Basic Science Fellowship Grant
Patrick Walsh, PhD
2004 AST Basic Science Fellowship Grant Keri Csencsits, PhD
2004 AST/Fujisawa Clinical Science Fellowship Grant Georffrey Camirand, PhD
2004 Fujisawa/AST President's Clinical Science Fellowship Grant
Elizabeth Sarah Herman, MD
2004 Fujisawa/AST Council's Clinical Science Faculty Grant
Lorenzo Gallon, MD
2004 AST/JDRF Fellowship Grant Christian Cruz, MD
2004 AST International Fellowship Grant
Martin Oberbarnscheidt, MD
2004 AST/Roche Basic Science Faculty Grant
Xueli Yuan, MD, PhD
2004 AST/Roche Basic Scientist Faculty Grant Indira Guleria, PhD
2003
2003 AST Council's Fellowship Grant David Tom Cooke
2003 AST/Novartis Fellowship Grant Eun D. Lee
2003 AST Basic Science Fellowship Grant Ashok Muniappan
2003 AST/Sangstat Fellowship Grant Syed Huq
2003 AST/Fujisawa Fellowship Grant Harini Chakkera
2003 AST President's Fellowship Grant Jun B. Lee
2003 AST Council's Faculty Grant Dympna Kelly
2003 AST Faculty Grant Amy Waterman
2003 AST/Roche Faculty Grant Rob Striker
2003 AST/JDRF Fellowship & Faculty Grant Mohammed Javeed Ansari
2003 AST/Women's & Minority Faculty Grant Anna Valujskikh
2003 AST/International Fellowship Grant Masonori Abe
2002
2002 AST Council's Fellowship Grant Xun-Rong Luo
2002 AST/Novartis Fellowship Grant Jonathan Maltzman
2002 AST Basic Science Fellowship Grant Anton Decker
2002 AST/Sangstat Fellowship Grant Yoshinobu Akiyama
2002 AST/Fujisawa Fellowship Grant Arjang Djamali
2002 AST President's Fellowship Grant Kristel Hunt
2002 AST Council's Faculty Grant Enver Akalin
2002 AST Faculty Grant Nader Najafian
2002 AST/Roche Faculty Grant Maria-Luisa Alegre
2002 AST/JDRF Fellowship & Faculty Grant Ramaniah Mamillapalli
2002 AST Basic Scientist Faculty Grant Soumitro Pal
2002 AST Women's & Minority Faculty Grant Anne VanBuskirk
2001
2001 AST Council's Fellowship Grant Anirban Bose
2001 AST/Novartis Fellowship Grant Robert Cina
2001 AST Basic Science Fellowship Grant Adam Schrum
2001 AST/Fujisawa Fellowship Grant Darshana Dadhania
2001 AST President's Fellowship Grant Yingyos Avihingsanon
2001 AST Council's Faculty Grant Markus Frank
2001 AST Faculty Grant Randall Sung
2001 AST/Roche Faculty Grant Ana Coito
2001 AST/JDRF Fellowship & Faculty Grant Dolca Thomas
2001 AST Basic Scientist Faculty Grant Andres Jaramillo
2001 AST Women's & Minority Faculty Grant Yolanda Becker
2000
2000 AST Faculty Development Grant Lisa Robinson
2000 Presidents Fellowship Grant Reza Abdi
2000 Novartis Fellowship Grant Nelson Goes
2000 Roche Faculty Grant Jennifer Woodward
2000 AST Council's Faculty Grant Eugenia Fedoseyva
2000 Fujisawa Fellowship Grant Biljana Pavlovic Surjancev
2000 AST Councils Fellowship Grant Dimitry Samsonov
1999
1999 Roche Faculty Grant Milan Kinkhabwala
1999 Novartis Fellowship Grant Markus Frank
1999 Faculty Development Grant Ana Coito
1999 Fujisawa Fellowship Grant Choli Hartono
1999 AST President's Young Investigator Andrew Wells
1999 Sangstat Fellowship Grant Hrefna Gudmundsdottir
1999 President's Fellowship Grant Stephen Alexander
1998
1998  Roche Faculty Grant Hugo Rosen
1998  President's Fellowship Anne Burke
1998  Novartis Fellowship Boris Nikolic
1998  Faculty Development Ashwani Khanna
1997
1997 Sandoz Juan Luis Contreras Rodriquez
1997 Sangstat Fellowship Ya Fen Chen
1997 Roche Investigator Faculty Grant Ginny Bumgardner
1997 Fujisawa Fellowship John Vella
1997 Ortho Faculty Grant Martha Pavlakis
1996
1996 Roche Investigator Faculty Grant Alfredo Fabrega
1996 Sandoz Fellowship Grant Milagros Samaniego
1996 UpJohn Investigator Diane Alexander
1996 Ortho Faculty Grant Ann Van Buskirk
1996 Fujisawa Fellowship Angeles Baquerizo
1996 President's Young Investigator Fellowship A. Singh
1996 Council's Young Investigator Tousif Pasha
1995
1995 Sandoz Fellowship Tomasz Kozlowski
1995 Ortho Faculty Grant Edward Geissler
1995 President's Young Investigator Meiko Toyodo
1995 Fujisawa Fellowship Grant Serhat Azizleri
1995 Council's Young Investigator Steven Katznelson

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