American Society of Transplant Physicians

ASTP 1998 ABSTRACTS

Plenary Session I

• Hla-G Expression Protects Porcine Endothelial Cells Against Natural Killer Cell Mediated Xenogeneic Cytotoxicity.
• Bcl-Xl Augments T Cell Survival In The Absence Of Costimulation And Blocks Immunosuppression With Ctla41g.
• Increased Intragraft Angiotensinogen Gene Expression In Post-Transplant Recurrent Fsgs
• A Randomised, Double-Blind, Plasma Concentration Controlled Study Of The Safety And Efficacy Of Oral Mycophenolate Mofetil For The Prevention Of Acute Rejection After Kidney Transplantation.
• Specific tolerance without demonstrable chimerism: an alternative paradigm
• Fas Ligand And Nk Cells Are Important Mediators Of Late Skin Graft Rejection
• Lung Allograft Function Correlates With The Pathway Of Donor Antigen Presentation: Maintenance Of Perlpheral Blood Donor Cells And Release Of Soluble Hla Of Donor Origin.
• Comprehenslve State Legislation Dramatically Increases Organ Donations And Transplantation

Concurrent Session 1: Kidney Transplantation: Cyclosporine Withdrawal and Kinetics

• Long-Term Evaluation Of Two Protocols Of Elective Cyclosporin Withdrawal In Renal Transplant Recipients
• A Meta - Analysis To Assess The Safety And Tolerability Of Two Formulations Of Cyclosporine: Sandimmune And Neoral
• Cyclosponne Withdrawal In Renal Transplant Recipients
• Race Effect In Cadaver Renal Transplants Induced With Full-Dose Cyclosporine Irrespective Of The Presence Of Delayed Graft Function
• Tacrolimus/"Low-Dose" Mycophenolate Mofetil Vs. Micro-Emulsion Cyclosporine/ "Low-Dose" Mycophenolate Mofetil After Kidney Transplantation - 1 Year Follow- Up Of A Prospective Randomized Clinical Trial
• Prevalence Of Chronic Allograft Nephropathy And Analysis Of Predictive Factors: Results Of 2-Year Protocol Biopsies From A U.S. Multicenter Study

Concurrent Session 2: Kidney Transplantation: Prognosis, Compliance, and Outcome

• Failure Of Non-Compliance To Predict Graft Survnal In Lrd Renal Transplantation: The Unos Experience
• Profiles Of Non-Compliance In Patients With A Functioning Renal Transplant- A Multi Center Study
• Prognosis Following Pi Mary Renal Allograft Failure
• Decreased Nephron Mass (Nm) Is Not Associated With Worsened Renal Survival, Function Or Proteinuria In Living Donor (Ld) Renal Transplants: A Model For Future Renal Transplantation (Rt)
• Diminished Levels Of Dehydroepiandrosterone-Sulfate In Long-Term Renal Transplant Patients Are Associated With Poorer Graft Function
• Kidney Transplantation In Older Patients With Renal Failure
• Predicting Outcome In The Elderly Renal Transplant Recipient
• Factors Influencing The Outcome Of Transplantation (Tx) In Older Esrd Patients (Pts) I E.. 60 + Years

Concurrent Session 3: Regulation of Lymphocyte Proliferation and Survival

• Interferon-Gamma (Ifny) Is Critical For Regulating The Proliferation Of Alloantigen-Activated T Cells
• Two Distinct Forms Of T Cell Anergy Are Induced By Lack Of Costimulation Vs. Cell Division During Primary Activation.
• The AT_1A Receptor For Angiotensin Ii Modulates T Cell Proliferation In Mixed Lymphocyte Cultures
• Examining Individual T Cells During An In Vivo Immune Response: How Does Cd28 Signalling Regulate Recruitment And Expansion?
• Visualization Of Antigen-Specific Cd4+T Cell-B Cell Interaction During A Primary Immune Response In Vivo.
• Antibodies To A Novel T Cell Antigen, Tirc7, Block Selectively Typ 1 But Not Typ 2 T-Cell Activation And Prolongs Allograft Survival
• The Effect of Endothelium on Th1 and Th2 Lymphocyte Apoptosis
• Allograt Rejection Of Fas And Fas-L Deficient Kidneys : Lack Of Correlation Between Improved Function And Apoptosis

Concurrent Session 4: Xenotransplantation I

• Antigen Painting To A Xenografted Heart's Content: Th2 Cytokine-Induced Changes In Proteoglycan Expression Result In Endothelial Coating By Host Mhc Class I And Regulators Of Complement Activation.
• Cd4-Mediated Islet Xenograft Rejection Requires `Indirect' Antigen Recognition
• Transplant Arteriosclerosis Of Longterm Cardiac Xenografts Is Blocked By Induction Of Hemoxygenase
• Costimulatory Pathways Are Active In Xenogeneic Immune Responses
• In Vivo Rejection Of Porcine Skin Grafts Is Mediated By Human Cd4⁺T Lymphocytes
• Altered Expression Of Rat Peripheral T-Cell Receptor Vp Repertoire In F344-To-B10 (Rat-To-Mouse) Mixed Xenogeneic Chimeras
• Role Of Regulatory Cells Developing In Porcine Thymus Grafts In Tolerance To Both Host And Donor Antigens
• Porcine Thymus Supports Development Of Functional Human T Cells

Concurrent Session 5: Liver Transplantation: Immunosuppression

• Tacrolimus Vs. Neoral® In Combination With Mycophenolate Mofetil And Low-Dose Steroids After Liver Transplantation
• Clinical Benefit Of Neoral Dose Monitoring With Cyclosporine 2-Hour Peak Levels Compared To Trough Levels In Stable Liver Transplant Patients
• Cyclosporine 2 Hour Blood Level: An Excellent Predictor Of The Area-Under-The-Curve In Liver Transplant Patients Treated With Neoral
• Comparative Pharmacokinetics Of Sang-35 Cyclosporine Versus Neoralt' In Stable Adult Liver Transplant Recipients.
• Multicenter, Randomized, Double-Blind Study On Efficacy And Safety Of Microemulsion Cyclosporine Versus Conventional Cyclosporine In Patients Receiving Primary Orthotopic Liver Allografts
• A randomized, double-blind study of Neoral vs. Sandimmune in primary liver transplant recipients with two year follow up
• The Canadian Prograf In Liver Transplant Trial: The One-Year Composite Outcome.
• Steroid Withdrawal Is Safe And Feasible In Stable Liver Transplant Recipients
• Acute Rejection Is More Common In Black Liver Transplant Recipients.

Concurrent Session 6: Pediatric Transplantation: Renal and Cardiac Studies

• Quality Of Life Of Children Post Transplantatlon Compared To Children On Dialysis.
• The Effect Of Different Immunosuf'pression Therapy On Erythropoietin Production In Renal Transplantation
• The Impact Of Donor Source, Pre Operative Immunotherapy And Prophylactic Antibody Therapy On First Rejection Episodes In Children
• Humanized Monoclonal Anti interleukin-2 Receptor (Il-2r) Antibody Daclizumab (Zenapax®) In Pediatric (Ped) Renal Transplantation (Tx)
• Post Transplant Dlabetes Mellitus In Pedlatrlc Renal Transplant Recipients: A Report Of The North American Pediatric Renal Transplant Cooperative Study (NAPRTCS)
• Recurrent Rejection In Pediatric Cardiac Transplantation.
• Experimental Transplantation Of Size-Reduced, Adult Kidneys Into Pediatric Recipients
• Cyclosporine Level Changes In Pediatric Renal Transplant (Tx) Patients During Growth Hormone Therapy
• Results Of Simultaneous And Sequential Pediatric Liver And Kidney Transplantation

Concurrent Session 7: Kidney Transplantation: Viral Infections in Renal Transplants

• Incidence Of Cmv Infections During Daclizumab Treatment In Renal Allograft Patients
• Clinical And Economic Impact Of Oral Ganciclovir Prophylaxis Of Cmv-Disease In Renal Transplantation
• Valaciclovir Reduces the Incidence of Cytomegalovirus Disease and Acute Graft Rejection in CMV-Seronegative Recipients of a Seropositive Cadaveric Renal Allograft
• Risk Factors And Human Herpes Virus-8 (Hhvb) During Kaposi's Sarcoma (Ks) In Kidney Transplant Patients
• Intensive Screening And Evaluation For Hepatitis C Virus (Hcv) In The Pretransplanted Esrd Patient
• The Long-Term Impact Of Hcv Infection In Renal Allograft Recipients

Concurrent Session 8: Organ Donation

• Organ Donation And Ethnicity: Predicting Support For Organ Donation Among Ethnic Minorities
• Role Of The Physician In Efforts To Boost Organ Donation Rates
• Effects Of Brain Death On Donor Organ Quallty Endothelial Cell Activation And Predisposition For Ischemia/Reperfusion Damage In Transplantation
• A Prospective, Randomized Multicenter Trial Comparing Celsior To Standard Cardiac Preservation Solutions
• The Mechanism Of Concanavalin A In Resuscitating Transplanted Failing Rat Hearts
• Protective Role Of Nitricoxideinischemia And Reperfusion Injury Of The Liver

Concurrent Session 9: Allorecognition/Alloantigen Presentation

• Characterization And Manipulation Of T Cell Responses To A Single Defined Minor Alloantigen
• Induction Of Autoimmunity After Heart Transplantation Is A Major Component Of The Rejection Process
• T Cell Costimulatory Blockade Suppresses Indirect Better Than Direct Alloimmune Responses In Vivo
• Acute Cd4mediated Cardiac Allograft Rejection Requires Donor Class II Mhc Molecules
• Soluble MHC class I Molecules abrogate T Cell Function
• Genetic Engineering Of Immature Dendrltlc Cells To Express Mammalian Il-10 Enhances Their Immunogencity
• Enhancement Of Dendritic Cell Tolerogenicity By Genetic Modification Using Adenoviral Vectors Encoding Cdna For Tgfb1

Concurrent Session 10: Xenotransplantation II

• Direct Recognition Of Miniature Swine Endothelial Cells By Human Cd8 T Cells Involves Both Xenogeneic Sla Class I Molecule And Associated Peptides.
• Transgenic Manipulation to Prevent Hyperacute Rejection of Xenografts: Triple Transgenic Mice and Pigs. Additive Effects of Complement Regulators and Suppression / Elimination of the a-Gal Epitope
• Prolonged Survival Of Hdaf Transgenic Pig Ktdneys In Primates
• Anti-HLA Antibodies Do Not Recognize Xenoantigens From DAF Transgeneic Pig Kidneys
• Identification Of Human Immunoglobulin Genes Involved In The Immune Response To Pig Tissues.
• Prolongation Of Heart Xenograft Survival In A Concordant Hamster To Rat Model Following Therapy With A Rationally Designed Immunosuppressive Peptide

Concurrent Session 11: Liver Transplantation: Donor Issues: Clinical Outcomes

• The Unos Expanded Donor Study: Results Of The Liver Analysis.
• The United States Liver Donor Population In The 1990s: A Descriptive, Population-Based Comparative Study
• Outcome Analysis Of Marginal Donor Liver Grafts Transplanted In Critically Ill Recipients-The Unos Registry Data 1991-1995
• Incidence Of End-Stage Red Failure Amongst Long-term Survival Of Primary Liver Transplant Recipients Under Tacrolimus: Adults and Children
• Domino Liver Transplantation for Familial Amyloidotic Polyneuropathy: Optimal use of a Scarce Resource
• Child's Class At Initial Evaluation Correlates With Survival To Liver Transplant
• Use Of 2-D Echo And Right Heart Catheterization For Diagnosis Of Pulmonary Hypertension In Patients Evaluated For Liver Transplantation
• Outcome Of Recurrent Autoimmune Hepatitis After Liver Transplantation
• Components Of Care Responsible For The Rising Costs Incurred During The Pre-Transplant Period In Liver Transplant Recipients

Concurrent Session 12: Heart Transplantation: Graft Arteriopathy in Heart Transplants

• Usefulness Of Urine Fibrinopeptide A Levels In Detecting Transplant Coronary Arteriopathy
• The Status Of Microvascular Antithrombin After Early Fibrin Deposition Is Associated With Outcome In Cardiac Transplant Recipients.
• Anti-Donor HLA Antibodies Associated With Allograft Arteriopathy Detected Using Intravascular Ultrasound
• Early Versus Late Onset Vascular Rejection In Cardiac Transplantation.
• Cholesterol Lowering After Heart Transplantation is Associated with a Lower Incidence of Transplant Coronary Artery Disease.
• Total Plasma Homocysteine Concentrations are Strongly Correlated with Whole Blood Cyclosporine Levels and Angiographic Coronary Artery Disease in Heart Transplant Patients.

Poster Session I: T-Cell/B-Cell Activation

• Effects Of Selective Cd28:B7-1 Blockade In Acute Cardiac Allograft Rejection
• Cd30 Expression Identifies A Novel Alloreactive T Cell Subset That Is Found Within Rejecting Allografts
• CD28 Costimulation Of Proliferation In Murine Splenic T Cells Is Sensitlve To Inhibition By SP100030, A Novel T Cell-Specific Dual Inhibitor Of NF-Kb and AP-1
• Inhibition Of Dihydroorotate Dehydrogenase (Dhodh) Is The Molecular Mechanism Of Immunosuppression By The Malononitrilamides (Mnas) In Vivo
• Mechanism Of Action Of Cyclosporine A (Csa) And Tacrolimus (Fk) On Calcineurin (Cn)
• Innate Immunity In Small Bowel And Heart Transplantation
• Nk Cells Comprise A Unique Entity Of Lymphocytes Which Act As An Important Efffector Arm Of The Innate Immune Response.
• Activation Of The Immune System In Patients After Cryopreserved Human Cardiac Valve Transplantation.
• Cyclosporine Resistant Cd28 Co-Stimulatory Pathway Inhibition With Curcumin May Be Due To Apoptosis
• Evaluation Of Impdh-Acivity In Whole Blood And Isolated Blood Cell Fractions For Monitoring Of Cell-Cept-Mediated Immunosuppression.
• Generalized Loss Of Tcr By Graft Infiltrating T Cells

Poster Session I: Allorecognition/Antigen Processing and Presentation

• Transduction Of Dendritic Cells Witb Adenoviral Vectors Encoding Ctla4-Ig Markedly Reduces Their Allostimulatory Activity
• Immunohistochemical Analysis Suggests That Acute Rejection Of Murine Cardiac Allografts Lacking Donor-Type Apcs Proceeds Via The Indirect PathwayDifferential Usage Of The Class Ii Transactivator (Ciita) Promoters In Viv0
• Studies Of Allograft Tolerance In Class I And Class Ii Mhc Deficient Transgenic Mice Without Immunosuppression
• Identification Of Class I Peptides Involved In The Indirect Pathway Of Allorecognition
• Modulatlon Of Immune Responses Induced By Gene Transduced Dendritic Cells
• Passenger Leukocytes From An Allogeneic Heart Graft Can Induce Lethal Lymphoid AplasiaInfluence Of Cryopreservation On Antigen Expression And Immunogenicity Of Human Vascular Endothelial Cell

Poster Session I: Cytokines/Chemokines

• Signals Transduced By The Common Y Chain Of Cytokine Receptors Are Critical In Allograft Rejection
• Cytotoxic T-cells are diminished during allograft rejection in mice deficient of Stat1 (signal transducer + activator of transcription)
• Early Intragraft Expression Of Chemmokine Genes During Acute Rejection Of Allogeneic Cardiac Grafts Objectives
• Ribavirin Treatment Of Recurrent Hepatitis C Virus (HCV) Following Liver Transplantation: Proposed Mechanism Of Action
• Chemokine Regulation of T Cell Entry Into Vascularized Allografts: A Central Role for Lymphotactin?
• Effect Of The Lazaroid U-74389g On Chemokine Gene Expression And Apoptosis In Renal Ischemia- Reperfusion Injury
• A Novel Nf-Kb Enhancer Region Regulates Cytokine Induction Of The Human Inducible Nitric Oxide Synthase (Inos) Gene Promoter
• Cmv Promoter Characteristics Determine Cytokine Sensitivity And Gene Expression In Adenovirus Mediated Gene Transfer
• In Vivo Migration And Scrwal Of Donor-DerivedDendritic Cell Progenitors Genetically Modified Using An Adenoviral Vector Encoding Cdna For Tgfb1
• Alleviation Of Graft Versus Host Disease By Inhibition Of Tnf Production Using Immunosuppressive Allotrap Peptides
• Constitutive Activation Of Cytokine Jak/Stat Signaling Pathway Proteins In Ebv-Transformed B Cell Lines From Patients With Ptld
• Downmodulation Of CXCR1 and CXCR2 In Human Neutrophhs By A Monoclonal Antibody To CD45RB
• Analysis Of The Intragraft Cytokine Network In Heart Transplant Patients Treated With An Anti-Cd25 Antibody
• Direct Effect Of Human Transforming Growth Factor-B₁ On Albumin Permeability Of Rat GlomerullIn Vitro
• Towards A Genomic Analysis Of Transplant Immunobiology And Related Phenomena
• FLT-3 Ligand Increases Microchimerism But Can Prevent The Therapeutic Effect-Of Donor Bone Marrow In Transiently Immunosuppressed Cardiac Allograft Recipients
• Tolerance induction in rat transplantation models by anti-CD4 mAb is associated with intragraft upregulation of IL-4 - but intragraft overexpression of IL-4 L is not sufficient for tolerance induction
• Chemokine Receptor Expression In Rejecting Human Liver Transplants
• Intragraft Expression Of Rantes Is Associated With Granzyme B And T Cell Mediated Cytotoxicity During Rejection Of Allogeneic Skin Grafts Objectives
• Expression Of Inos In Acute Human Renal Allograft Rejection
• Urinary Cytokine Patterns In Renal Allograft Recipients

Poster Session I: Chronic Rejection

• CD28:B7 Blockade Prevents Transplant Vasculopathy And Mononuclear Cell Infiltration In A Fully Allogeneic Cardiac Transplant Model
• Recipient Mesenchymal Cells Infiltrate And Remodel Medial And Adventitial Tissue In The Rat Femoral Artery Allograft Model Of Chronic Vascular Rejection
• Prevention Of Obliterative Airway Disease (Oad) Without Immunosuppression In Heterotopic Rat Tracheal Allografts: Anastomosis Of Recipient Trachea To Donor Trachea Enables Re-Epithelialization Of Allografts By Recipient Eplthelium
• Lung Epithelium-Derived Il-10 Stimulates Lung Fibroblast Proliferation In Vitro: Implications For The Pathogenesis Of Obliterative Bronchiolitis After Lung Transplantation
• CD4 And CD8 Contribute Independently To Vascular Thickening: Insights From CD4-Knockout Recipients
• Induction Of Proteln Tyrosine Phosphorylation By Toxin-Conjugated Anti-Cd3 Antibodies
• Combined Therapy With Pravastatin (Pvs) And Cyclosporin (Cs) Decreases Arterial Intimal Thickening In A Modelof Severe Vascular Immune Injury
• Hearts Lacking Donor-Type Antigen Presenting Cells Develop Cardiac Allograft Vasculopathy
• Cytomegalovirus (Cmv)-Accelerated Transplant Vascular Sclerosis (Tvs): Requirement For Alloreactivity
• Cytokines Associated With Macrophages But Not T Cells Stimulate Endothelin-1 Peptide Secretion In Human Endothelial Cells And Glomerular Mesangial Cells.
• A Molecular Mechanism For The Direct Antiproliferative Effect Of Malononitrilamides (Mnas) On Vascular Smooth Muscle Cells.
• Cold Ischemia Induces Chronic Transplant Dysfunction In Rat Renal Transplants.
• Rat Allograft Coronary Vessels Switch To Secreting Angiogenic Proteins Post- Transplantation: Possible Therapeutic Role Of Platelet-Activating Factor (Paf) Antagonist
• Donor-Reactive Alloantibody Production Correlates With Neither Allograft Survival Nor Development Of Transplant Vascular Sclerosis (TVS)
• Effect Of Antioxidant Vitamins On Transplant Atherosclerosis In The Zucker Rat Model: Evidence For Oxidative Stress In The Pathophysiology?
• The Effect Of Immunosuppressants On The Development Of Chronic Rejection In Rat Aortas
• Nitric Oxide Stimulates Expression Of MHC Class II HLA-DR Molecules In Cultured Human Vascular Endothelial Cells
• Heat Shock Protein Expression And T-Cell Reactivity In Rat Cardiac Allografts Undergoing Chronic Rejection

Poster Session I: Animal Models

• Injection Of Plasma Protein Fraction From Patients With FSGS Causes Transient Proteinuria In Rats
• Transvivo Analysis Of Human Delayed Type Hypersensitivity
• Mmunohistochemical Analysis Of WKY>F344 Rat Skin Allografts And Cytokine Gene Expression In Draining Lymph Nodes: Comparison Of Immunocompetent Animals To Animals Tolerized With Donor-Specific Lung Allografts
• Reversal Of Diabetes In Streptozotocin-Treated Rats By Intramuscular Injection Of Recombinant Adeno-Associated Virus Containing Rat Preproinsulin II Gene
• Monitoring Of Pharmacodynamics (PD), But Not Pharmacokinetics (PK), Differentiates The Relative Immunosuppressive Potencies Of Leflunomide And Its Malononitrilamide (MNA) Analogs
• Rejection Of Human Islet Grafts By Human Leukocytes In NOD-SCID Mice

Poster Session I: Tissue Injury

• Use Of ET, And ET A +B Receptor Antagonists In Attenuating Hepatic Ischemia / Reperfusion Injury
• Interleukin-Lb Stimulates Endothelin-1 Gene Transcription And Endothelin Converting Enzyme Activity In Human Endothelial Cells
• Antibodies Eluted From Acutely Rejected Renal Allografts Bind To And Activate Human Endothelial Cells
• FAS-Mediated Cytotoxicity Is Not Required For Recurrence Of Autoimmune Diabetes In NOD Mice

Poster Session I: Basic Science

• Construction of a Recombinant Adenovirus Vector Encoding Fas Ligand With An Inducible System
• Anti-HLA Antibodies and Rejection Treatment Modality Both Strongly Influence Graft Outcome In High Risk Corneal Transplant Recipients
• Cytoprotection Induced By Genetic Modification Of Human Endothelial Cells (Ec) During Cold Preservation With An Adenovirus Vector Encoding The Anti-Apoptotic Bcl-2 Gene.
• Analysis Of Passenger Cell Composition Of Human Fetal Pancreas: Implications For Transplantation
• Molecular Cloning, Expression And Characterization Of Rhesus Macaque Fas Ligand Cdna
• An Immunologic Study Of Liver Failure Patients Bridged With Hepatocyte Infusions
• Expression Of A Gpi-Anchored, Single-Chain Antibody Specific For A Cell Death Signaling Domain Of Human Class I Mhc
• Inactivation Of The Al-3 Galactosyltransferase Gene Protects Murine Hearts From Xenoantibody-Dependent Human Nk Cell / Monocyte Mediated Injury
• Induction of IMPDH Activity After Long-Term Treatment With Mycophenolate Mofetil
• An Improved Technique For Isolating Pig Islets: The Importance Of Tensegrity In Islet Long Term Culture Viability

Poster Session I: Liver/Intestinal

• Incidence, Severity, and Outcome of Recurrent Hepatitis C is Similar in Patients Immunosuppressed With Neoral® and Sandimmune®
• Withdrawal of Prednisone from Orthotopic Liver Transplant Recipients with Hepatitis C Infection
• Class I And II Expression And Cytokine Release After Antigen Challenge Is Abnormal For Hepatitis C Individuals
• Increased Risk Of Post-Transplant Lymphoproliferative Disease In Recipients Of Liver Transplants With Hepatitis C.
• Quality Of Life And Functional Status Of Liver Transplant Recipients With Recurrent Hepatitis C Virus (Hcv) Hepatitis.
• Intrahepatic Bile Duct Necrosis As A Cause Of Allograft Failure In Patients Transplanted For Hepatitis C.
• Hepatitis C Related Glomerulonephritis: A Growing Cause Of Renal Failure After Liver Transplantation
• Lamivudine Therapy Prophylaxis And Rescue In Liver Transplant Patients
• Long-term, Low Dose, Passive Immunoprophylaxis with HBIg Effectively Prevents Recurrence of Hepatits B Infection after Liver Transplantation
• Evolution of Prevention and Treatment of Post-Liver Transplant HBV Recurrence
• Orthotopic Liver Transplantation (OLT) For Hepatocellular Carcinoma (HCC) in Patients With Chronic Hepatitis B Virus (HBV) Infection
• Liver Transplantation For Hepatocellular Carcinoma
• Surviving Posttransplant Lymphoma In The Liver Transplant Recipient: Cause For Optimism?
• Pro-Inflammatory and TH-1 Cytokine Profiles In Liver Transplant Patients Who Reject After OKT3 Induction
• Histopathological Features of Hepatic Allograft Rejection in Living-Related Liver Transplant Recipients
• Comparison Of Quadruple Induction Including Atg Or Il-2 Receptor Antibody With Fk506-Based Therapy After Liver Transplantation
• Conversion From Cyclosporine A To Mycophenolate Mofetil In Liver Transplant Recipients With Renal Function Impairment
• Relationship Between Calcineurin Activity And Cyclosporine Pharmacokinetics In Stable Liver Transplant Patients Treated With Neoral
• Costs of Cyclosporine (NEORAL®) and Tacrolimus (PROGRAF®) in the First Year After Liver Transplantation (OLT)
• Immunization, Screening for Malignancy, and Health Maintenance in the Liver Transplant Recipient
• Successful Outcome After Liver Transplantation Of Patients With High-Risk Pretransplant Psychosocial Evaluation.
• Quality Of Life Of Liver Transplant Recipients With Alcoholic Cirrhosis Compared To A Non-Alcoholic Sample.
• Adaptation Of The Mayo Primary Biliary Cirrhosis Model For Minimum Listing Criteria For Liver Transplant Candidates.
• Complications Of Percutaneous Liver Biopsy In Liver Transplant Patients
• Does Diabetes Mellitus Influence Liver Transplant Outcomes?
• Oxalosis: Stratifying Disease Severity and the Role of Organ Transplantation
• Is Pre-Liver Transplant Obesity A Risk Factor For Posttransplant Metabolic Complications?
• Malnutrition Affects Liver Transplant Outcomes
• Kidney Transplantation After Liver Transplantation. A Single Center Experience.
• Pilot Study of Recombinant Growth Hormone (GH) Administration Following Liver Transplantion
• Significance Of Portal Blood Flow Diversion In Auxiliary Partial Orthotopic Liver Transplantation For Metabolic Liver Disease
• Use Of Transjugular Intrahepatic Portosystemic Shunt As A Bridge To Transplantation In Budd- Chiari Syndrome.
• Reduction of Reperfusion Injury with Prostacyclin 12 after Liver Transplantation
• Functioning Hepatocyte Mass in Liver Allografts Assessed by^99mTc-Gsaliver Scintigraphy

Poster Session I: Ethics and Economics

• An Economic Evaluation Of Baxiliximab (Simulecttm) For The Prevention Of Acute Rejection In Renal Allograft Recipients
• The Cost Of Cmv-Disease In Renal Transplantation
• Pharmacokinetic Analysis Of Mycoprenolate Mofetil Versus Azathioprine In Cadaveric Renal Transplantation
• The Incidence And Costs Of Steroid-Related Side Effects In Renal Transplantation
• Long Term Resource Utilization And Economic Outcomes Analysis After Bladder-Drained Pancreas- Kidney Transplantation (Bd-Spk)
• Clinical Determinants Of Health Related Quality Of Life (Hrql) In Solid Organ Transplant Recipients
• Reliability And Cost Effectiveness Of Baseline Spirometry For Evaluating Pulmonary Function In Patients With Advanced Heart Failure Being Considered For Orthotopic Heart Transplantation.
• The Cost Of Rejection In Liver Allograft Recipients
• Utilization Of A Donor Registry

Poster Session I: Acute and Chronic Rejection

• Diagnostic Accuracy of Cytotoxic Lymphocyte (CL) Gene Expression in Peripheral Blood Leukocytes (PBL): Correlation with Rejecting Renal Allografts
• Anti-Donor Antibody Production And Development Of Chronic Rejection In Renal Transplants
• Correlation Between Banff Criteria And Outcome At 12 Months Following Acute Rejection In Multicenter Randomized Trial
• Pcna +Ve Mononuclear Cells In A 6 Month (Mo) Protocol Biopsy Associate With Long-Term Allograft Function.
• Clinicopathologic Features Of Untreated Borderline Changes By The Banff Criteria In Renal Allograft Biopsies.
• Determinants Of Renal Insufficiency In Chronic Renal Allograft Rejection
• Decreased Expression Of Transforming Growth Factor-Beta (Tgf-B) In Biopsies With Chronic Allograft Nephropathy After One Year Of 50% Cyclosporine Level Reduction And Mycophenolate Addition
• Is Perforin (P) Expression By Peripheral Blood Lymphocytes (Pbl) A Parameter Of Acute Graft Rejection (Agr) ?
• The Pathophysiology Of Acute Human Renal Allograft Rejection

Poster Session I: Kidney Trials and Outcomes

• Cyclosporine Monotherapy In Primary Living Donor Renal Allograft Recipients
• Improved Outcome Of Steroid Withdrawal In Mycophenolate Mofetil Treated Primary Cadaverlc Renal Transplant Recipients
• Steroid Wlthdrawal May Compromise Long Term Outcome After Kidney Transplantation
• A Randomised Study On The Effects Of Conversion Of Cyclosporine/Prednisone To Cyclosporine/Azathioprlne 6 Months After Kidney Transplantation
• Tacrolimus Therapy For Refractory Acute Renal Allograft Rejection: Differential Responses In African-Americans And Caucasians.
• Conversion From Liquid To Solid Sirolimus Formulations In Stable Renal Allograft Transplant Recipients.
• Multiple-Dose Pharmacokinetics Of The Immunosuppressant SDZ RAD In Stable Renal Transplant Patients
• Long-Term Results Of Mizoribine-Treated Renal Transplant Recipients – A Prospective, Randomized Trial Of Mizoribine And Azathioprine Under Cyclosporine-Based Immunosuppression
• Withdrawal Vs Continuous Cyclosporine A (Csa) Therapy In Kidney Transplant Recipients Of Haploidentical Donors.
• Single Center Analysis Of The Incidence Of Acute Rejection In Cadaver Renal Allograft Recipients Induced With Low Dose Okt3 With And Without Mycofenalate Mofetil (Mmf)
• Benefits Of Preemptive Dose Reduction For Sandimmune To Neoral Conversion In Stable Renal Transplant Recipients
• ATGAM™ Levels In Kidney Transplant Patients Treated For Acute Rejection
• Prednisone-Mycophenolate Mofetil Double Therapy For Cyclosporine A Toxicity In Kidney Transplantation
• A Phase I Study: The Side-Effect Profile Of An Intercellular Adhesion Molecule-L Antisense Phosphorothioate Oligodeoxynucleotide, Isis 2302.
• Tacrolimus Therapy For Refractory Acute Renal Allograft Rejection: A Four Year Experience With An Aggressive Approach
• Meta-Analysis of Tacrolimus and Mycophenolate Refractory Rejection Trials in Renal Transplantation
• Pharmacokinetics of Tacrolimus (FK506) in Various Conditioning Renal Transplant Recipients
• Randomised Trial Comparing Conversion Of Maintenance Treatment With Cyclosporlne And Prednisone To Azathioprine Or Mycophenolate Mofetil With Prednisone One Year After Kidney Transplantation.
• Lack Of Bioequivalence Of Two Sandimmune® Cyclosporine Formulations In Renal Transplant Patients Who Absorb Cyclosporine Poorly
• Extended Follow-Up And Pharmacokinetic Analysis Of Renal Allograft Recipients Treated With Fk506 (Fk) And Mycophenolate Mofetil (Mmf) As Primary Immunosuppression Following Kidney Transplantation
• Antibody Induction In The Current Era
• Variability In Cyclosporine Exposure Can Be Significantly Reduced In Stable Kidney Transplant Patients
• Clinical Impact Of Chimerization On The Immunogenicity Of T-Cell Antigen Monoclonal Antibodies In Renal Transplantation
• Disposition Of Basiliximab, A Chimeric Il-2 Receptor(Cd25) Monoclonal Antibody, In Pediatric Renal Transplant Patients
• Neoral, Cellcept, Prednisone (Ncp) Vs Neoral, Imuran, Predisone (Nip) In Cadaver Kidney Transplantation
• A Series Of Comparative Trials Between Sang-35 And Other Cyclosporine (Csa) Formulations In Stable Renal Transplant Patients (Pts)
• Induction Therapy With Polyclonal Atg Improves Long-Term But Not Short-Term Outcome Of Cadaver Renal Allografts

Poster Session I: Histocompatibility and Immunogenetics

• A Limited Number Of Hla Epitopes Are Related To Allograft Loss.
• Assignment Of Class 1 Cross Reactive Group (Creg) By Dna Typing: Laboratory Detection By Pcr-Ssp Of Creg For Matching In Clinical Transplantation
• Evidence That A 36kd B2m Associated Shla Is Derived From B2m-Free Hla Heavy Chains Cleaved From Activated Cells By Metalloprotease
• Matchng Of Cross Reactive Antigen Groups In Renal Transplantation: Non Unos, Single Centre Study
• Analysis Of Immunogenetic Factors For The Longer Waittng Time Experienced By Black Esrd Patients.
• Detrimental Influence Of A Historic Positive But Current Negative Ahg T Cell Igg Crossmatch On Graft Outcome In Cadaveric Renal Transplantation.
• Influence Of A Positive Historical Antihuman Globulin Crossmatch On Long Term Kidney Allograft Survival.
• Comparison Of Antibody Screening Methods Using Flow Cytometry With Cells Or Immobilized Purified Hla Antigens
• Bcl-2 Does Not Prevent Rejection Of Allografts In A Mouse Model Of Heterotopic Heart Transplantation
• The Hla Class I Deficient Burkitt Lymphoma Cell Line Daudi Fails To Express Gpi-Anchored Cell Surface Proteins.
• Rapid Definition Of Antibody Specificity By Elisa

Poster Session I: Organ Procurement, Preservation, and Allocation

• Donor Action: An International Programme To Assist Hospitals Increase Organ Donation
• An Alternative Approach To Evaluating Opo Performance
• A Centralized Histocompatibility Laboratory Allows Reduction In Cold Ischemja Time And Occurrence Of Acute Tubular Necrosis In Cadaveric Renal Transplants
• Donor/Recipient Traits Impact Long Term Renal Allograft Function Independent Of Rejection
• Race A Critical Factor In Organ Donation, Patient Selection, And Orthotopic Liver Transplantation?
• Ionized Calcium Concentration In Machine Perfusate Predicts Early Graft Function In Extended Criteria Donor Kidneys
• High [K'] Solutions Do Not Penetrate The Hepatic Paren-Chyma And Are Detrimental For Liver Graft Survival
• Increased Endothelin-1 Production During Cold Ischemia In Steatotic And Nonfunctional Human Liver Allografts May Indicate Enhanced Susceptibility To Ischemia-Reperfusion Injury
• Severity Of Illness Among Long Waiting Liver Transplant Candidates In An Organ Poor Region
• A Novel Hydroxyl Radical Scavenger, Nicaraven, Attenuates Ischemia Reperfusion Injury Of The Liver
• Transplantation (Ltx) In The Uw-Era Late Effects Of Cold Ischemia And Primary Dsyfunction
• Gadotinium Chloride Induced Blockade Of Kupffer Cells (Kc) Ameliorates Ischemialreperfusion (I/R) Injury In The Steatotic Liver.
• In Vivo Ischemia-Reperfusion Injured Rat Hearts Sustain Long Term Preservation And Transplantation
• Improved Myocardial Preservatton With Celsior And A Mutant Superoxide Dismutase
• Donor Demographic Changes And Transplantable Organs

Concurrent Session 13: Kidney Transplantation: Cardiovascular and Bone Complications

• Continued Loss Of Bone Density One Year Post Kidney Transplant Despite Preemptlve Therapy
• Risk Factors For Steroid Induced Bone Disease In Renal Transplantation
• The Incidence And Management Of Osteoporosis, Gout, And Avascular Necrosis In >20-Year Renal Allograft Recipients (Level 5a) Treated With Prednisone And Azathioprine
• Pharmacologic Variability Of Every Other Day (Qod) Glucocorticoid Therapy In Renal Transplant Recipients (Rtr)
• Native Peripheral Vascular Disease Contributes To Renal Transplant Renovascular Disease
• Perioperative Cardiac Morbidity In Renal Transplant Recipients: Incidence And Risk Factors.
• Prospective Pretransplant Ultrasound Screening In 206 Patients For Acquired Renal Cysts And Renal Cell Carcinoma.

Concurrent Session 14: Kidney Transplantation: Immunology: New Drugs and Risk Factors

• Paradigm Lost: Il-10 Is A Superior Correlate Of Acute Rejection Of Human Renal Allografts Compared To Thl Cytokine Ifn-Y.
• Safety And Tolerability Of The Immunosupressant SDZ Rad In Stable Renal Transplant Recipients
• Recombinant Human Tumor Necrosis Factor Receptor Fc Fusion Protein (Tnfr:Fc) Therapy In Kidney Transplant Recipients Receiving Okt3 Induction Therapy
• Use Of Pre-Transplant Mlc Immunoassay To Estimate The Risk Of Acute Rejection After Kidney Transplant
• Elisa Spot Detection Of Interferon Gamma And Interleukin 5 Producing Cells As A Predictive Marker For Renal Allograft Failure.
• Failure Of Donor Specific Transfusion (Dst) To Improve Long Term Outcome In Living Donor Kidney Transplant Recipients Treated With Cyclosporine: A 12 Year Retrospective Study From Seopf
• Anti-Phospholipid Antibody Syndrome And Post-Transplant Renal Thrombosis
• National Transplantation Pregnancy Registry: Pregnancy Outcomes In Female Kidney Recipients Treated With Cyclosporine Microemulsion (Neoral) Or Tacrolimus Vs. Cyclosporine

Concurrent Session 15: Mediators of Tissue Injury

• C6 Produced By Macrophages Contributes To Cardiac Allograft Rejection
• Alloimmune-Mediated Apoptoris During Acute And Chronic Rejection Of The Transplanted Heart
• NOS2 Induces Apoptosir During Acute Cardiac Rejection: Analysis Of In Vivo Pathways In NOS2-Knock Out Mice
• Analysis Oft Cell Dependent Nitric Oxide Production By Murine Macrophages
• In Vivo Imaging Of Apoptosis During Cardiac Allograft Rejection Using Radiolabeled Annexin
• Role Of Tgfb1 And Il-Io In The Immunoregulatory Effect Of Allogeneic Cd34t Cells
• TGF-B Mimics And Anti-TGF-B Reverses The Fibrogenic And Nephrotoxic Effects Of Cyclosporine
• Genetically Modified Cd34+ Cells As Vectors For In Vivo Gene Delivery To Areas Of Angiogenesis.
• Cytoprotection Of Pancreatic Islets (Pi) In Culture By Genetic Modification With The Anti-Apoptotic Bcl-2 Gene
• Reduction Of Ischemia/Reperfijsion Injury To The Liver By Gene Transfer Of The Anti-Apoptotic Bcl-2 Gene With An Adenoviral Vector
• Genetic Modification Of Liver Grafts With An Adenovirus Encoding Bcl-2 For Improved Organ Preservation.

Concurrent Session 16: Tolerance I

• Donor Resting B Cells Induce Indefinite Prolongation of Fully Allogeneic Cardiac Grafts When Delivered with Anti-IgD n- Monoclonal Antibody
• Mycophenolate Suppresses Nitric Oxide (No) Production During Antilymphocyte Therapy In Renal Allograft Recipients
• Blockade of CD40LICD40 costimulatory pathway in a DST pre- sensitization model of islet allograft leads to a state of allo-Ag specific tolerance and permits subsequent engraftment of donor strain islet or heart allografts
• Enhancement Of Immature Dendritic Cell Tolerogeniuiy By Administration Of Anti-CD40 Ligand Mab Is Associated With T Cell Apoptosis Not Inhibition Of Bl Molecule Expression
• High Levels Of Stable Multi-Lineage Hematopoietic Cbimerism And Donor-Specific Allogeneic Skin Graft Tolerance With T-Cell Costimulatory Blockade
• Creation Of Mixed Bone Marrow Chimera By Sub- Lethal Irradiation And Combined Blockade Of Cd28/B7 And CD40/CD40l Costimulatory Pathways
• Ctla4ig Reduces The Dose Of Radiation Required To Achieve Mixed Hematopoietic Chimerism And Donor Specific Transplantation Tolerance In Rats
• Short- And Long-Term Engraftment-Potent Of Mobilized Facilitating Cells And Hematopoietic Stem Cells Across Mhc-Barriers
• Allogeneic Thymokidney Transplants Induces Stable Tolerance In Miniature Swine
• Long Term (10 Month) Pig Islet Xenograft (Pix) Tolerance Using Measured-Total Lymphoid Irradiation, Splenectomy Short Term Rabbit Antithymocyte Globulin And Deoxyspergualin Without Chronic Immunosuppression
• Reversal Of Naturally Occurring Insulinopenic Diabetes And Induction Of Isolated Islet Xenograft Tolerance In A Pre-Clinical Study
• Tolerability And Side Effects Of Anti-Cd3 Immunotoxin (Acd3-It) In Preclinical Testing In Kidney Allograft Recipients
• Early Systemic Immunologic Factors Associated With Induction Of Long Term Renal Allog& Tolerance Without Maintenance Immunosuppressive Drugs
• Evidence For Renal Transplant Tolerance To Non- Inherited Maternal Antigens (Nima) In 1 Hla- Haplotype Matched Siblings: A Multicenter Study

Concurrent Session 17: Organ Donation: Kidney Issues

• Are Wedge Biopsies Of Cadaveric Kidneys Obtained At Procurement Reliable?
• Transplantation Rate Of The Blood Group B Waiting List Is Increased By Using A₂ And A₂b Kidneys
• Risk Factors For Renal Allograft Survival From Pediatric Cadaver Donors
• Is There A Difference In The Quality Of Kidneys That Are Offered For Payback Compared To Non-Payback Kidneys?
• Exchange Donor Program In Kidney Transplantation
• Evaluation Of Renal Function In Potential Living Related Donors (LRD).
• A Comparative Study Of Conventional And Minimally Invasive Open Living Donor Nehrectomy
• Laparoscopic Vs. Open Live Donor Nephrectomy: A Multivarmte Patient Outcomes Analysis
• A 12 Year Single Center Experience Of 100 Renal Transplants With Non-Heartbeating Donor Grafts
• Prostaglandin E1 Improves Perfusion Characteristics And Early Graft Function In Extended Criteria Donor Kidneys
• A New Technique for Direct Analysis of Reperfusion Mechanisms after Lung Ischemia
• Clinical And Economic Implications Of Using Anti- Hbc-Positive Donors For Lwer Transplantation

Concurrent Session 18: Pediatric Transplantation: Liver Studies

• Clinical Impact Of Titrated Withdrawal Of Immunosuppression In Pediatric Liver Transplant Recipients
• Pediatric Liver Transplantation: From The Full-Size Liver Graft (Fs) To The Reduced (Red), Split And Living Related Liver Transplantation (Lrt)
• Liver Transplantation As Treatment For Hepatocellular Malignancy In Children
• Variables Affecting The Risk Of Cmv Infection Or Seroconversion In The Unexposed Pediatric Liver Transplant Recipient
• Strategy To Reduce The Incidence And Mortality Of Posttransplant Lymphoproliferative Disease After Liver Transplantation In Children
• Survival And Morbidity After Full Size, Partial And Split Liver Transplantation In Children
• Long-Term Outcome And Complications Of Living Related Liver Transplantation (LRLT) In Children With Intrapulmonary Shunting
• Incidence, Management, And Outcome Of Serious Pancreatitis Following Pediatric Liver Transplantation
• Transplantation Of Pediatric Patients With Fulminant Hepatic Failure: Improved Survival With Utilization Of Segmental Allocrafts From Live Donors.
• An Analysis Of Pretransplant Variables Associated With Long-Term Graft Outcome In Pediatric Liver Tp.Ansplant Recipients Receiving Primary Tacrolimus Therapy
• Primary Liver Transplantation In Children Under Tacrolimus:3 To 8 Years Actual Follow-Up
• Conversion Of Pediatric Liver Allograft Recipients From Cyclosporin To Tacrolimus Based Immunosuppression: 4 To 8 Years Follow-Up

Plenary II

• Intrarenal Expression Of Cytotoxic Attack Molecules During Acute Rejection Of Renal Allografts In Pediatric Recipients
• A Multivariate Analysis Of The Causes Of Racial Disparities In The Living Related Donor Renal Transplant Population:The Unos Experience
• Interruption Of CD40/D40l Co-Stimulation Alters Intragraft Chemokine Expression: Rejection Is Linked To CXCR3+ Cells And Ligands IP-10 And MIG Whereas Long-Term Survival Is Associated With Their Suppression And Infiltration By CCCR2+ Cells.
• Elimination Of Antibody Responses Inhibits Acute And Chronic Cardiac Allograft Rejectjon In Mice.

Concurrent Session 19: Kidney Transplantation: Delayed Graft Function and Post-transplantation Diabetes Mellitis

• Delayed Graft Function Predicts Long-Term Kidney Graft Survival Independent Of Early Acute Reiection Or Discharge Creatinine
• Expression Of LFA1 In Biopsies Of Kidney Recipients Treated With An Anti-LFA1 Monoclonal Antibody. Correlations With Delayed Graft Function
• The Rate Of Decline In Renal Function In Chronic Allograft Rejection (Fibrosis) Can Be Predicted By Intratubular Levels Of Transforming Growth Factor Beta (TGFB)
• Diabetes Mellitus With Neoral (Cyclosporine) Vs. Prograf (Tacrolimus) Based Regimens After Kidney Transplant
• Late Onset Post-Transplant Diabetes In Hyperlipidemic Renal Transplant Recipients: Predictive Value For Glucose Area-Uner-The-Curve (Glu-Auc) And Natural History Ofinsulinresponse To Meal.
• De Novo Insulin-Dependent Diabetes Mellitus In Living Kidney Transplant Recipients Under Tacrolimus Immunosuppression.
• Succesful Transplantation Without Recurrence In Hemolytic Uremic Syndrome Omitting Calcineurin Inhibitors For Immunosuppression
• Inferior Outcome Of Cadaveric Kidneys Preserved >24 Hrs In Histidine-Tryptophan-Ketoglutarate (Htk) Solution

Concurrent Session 20: Pancreas and Islet Transplantation

• Clinical Experience With Autologous And Allogeneic Pancreatic Islet Transplantation
• A Multivariate Analysis Of Matching And Graft Survival In Spk Transplantation: The Unos Experience
• Fate Of Type I Diabetics Whose Grafts Fail After Kidney Or Simultaieous Pancreas-Ktdney Transplants
• The Impact Of Hypoalbuminemia In Simultaneous Kidney- Pancreas Transplant Recipients
• Estimating Quality Of Life In Uremic Iddm Patients For The Purpose Of Medical Decision Analysis
• Posttransplant Infection In Enteric Vs Bladder-Drained Simultaneous Pancreas-Kidney (SPK) Transplants
• Effect Of Combined Kidney-Pancreas Transplant On The Lipid Profile: One Year Follow-Up
• Pretransplantation Insulin Dose As An Indicator Of Hyperglycemia Following Pancreatic Transplantation
• Allograft Pancreatectomy After Pancreas Transplantation: A Comparison Of Systemic- Bladder Versus Portal-Enteric Drainage.
• Preliminary Experience With Midodrine (Proamatine) W Kidney/Pancreas Transplant Patients Experiencing Orthostatic Hypotension
• Mri Is Superior To Angiography For Living Related Simultaneuous Pancreas And Kidney (Spk) Donation
• Myofibroblasts Expressinga-Smooth Muscle Actin In Grafti Pancreatitis.

Concurrent Session 21: Experimental Immunosuppression I

• Two Donor Polymorphic Amino Acids (S₇₇ And N₈₀) Form A Tolerogenic Epitope That Induces Donor - Specific Transplantation Tolerance In Rats
• In Vitro And In Vivo Immmunomodulatory Effects Of Rdp 1258, A Novel Synthetic Peptide
• Prolongation Of Rat Allograft Survival Following Therapy With Rationally Designed Immunosuppressive Peptides: Analysis If The Mechanism Of Action
• A Murlne Transgenic Model Of Human Class I Mhc- Mediated Programmed Cell Death
• Anti-Mhc Class Ii Mabs Supress Allogenic Responses In Solid Organ Transplantation In Mice And Primates
• Prophylaxis Of Renal Allografts From Rejection By Fty720 In Cynomolgus Monkeys Treated With Subtherapeutic Doses Of Cyclosporine
• Pharmacokinetics Of Iv Administered Murine Anti-Human B7.1 And Murine Anti-Human B7.2 In Cynomolgus Monkeys
• Effects Of Anti-Cd2 Monoclonal Antibody: Cd2 And Cd95-Mediated Apoptosis Of Human Peripheral T Cells.

Concurrent Session 22: Chronic Rejection I

• Chronic Cardiac Allograft Rejection Is Independent Of Donor Mhc Class Ii Antigens
• Characterization Of Mhc Allopeptide Reactive T Cell Clones From Human Renal Allograft Recipients
• Alloantibodies Are Not Required For Development Of Transplant Vascular Sclerosis
• Evidence Against The Role Of Th1 In The Development Of Chronic Cardiac Allograft Rejection
• Il-10 And Ifn-Y Mediate Cardiac Allograft Vacsular Changes: Insights From Il-10 Knockout Mice
• Transforming Growth Factor Beta Plays A Critical Role In Chronic Rejection
• Immune Sources Of Tgf-Bi Protect Against Graft Vasculopathy: Graft Vascular Remodeling In Tgf-Bi-Deficient Mice
• Anti-Proliferative Effects Of Pravastatin (Pvs) And Cyclosporin (Cs) On Vascular Smooth Muscle Cells (Vsmc) - Is Inhibition Of Ras Activity Themechanism?

Concurrent Session 23: Cytokines

• Disruption Of Il-4 Responses In Stat 6-Knock Out Mice Does Not Alter Graft Vasculopathy
• Contribution Of Ifn-Y To Acute Allograft Failure In Murine Cardiac Transplants: Role In Vascular Thrombosis
• Il-2 + Interferon-Y Double Knockout Mice Reject Heterotopic Cardiac Allografts
• Type 2 Immune Deviation Dlfferentially Affects Alloreactive Cd4+ And Cd8+ T Cells But Does Not Alter Their Ability To Mediate Skin Graft Rejection
• Type 2 Immune Deviation Dlfferentially Affects Alloreactive Cd4+ And Cd8+ T Cells But Does Not Alter Their Ability To Mediate Skin Graft Rejection
• Immune Nonresponsiveness To Cardiac Allografts By Intrathymic Inoculation Of Donor Class I Allopeptides Is Associated With High Levels Of Transcripts For Th2 Cytokines In The Graft
• Prolongation Of Organ Allograft Survival By Systemic Anti-Il-10 Antibody Administration Is Mediated By B Cell Suppression
• Identification Of Sequences Involved In Internalization And Degradation Of The Common Cytokine Receptor Y_c Chain
• Rapamycin (Rapa) Enhances Transforming Growth Factor Beta (Tgf-B₁) Expression In Immortalized Rat Proximal Tubules Cells (Irptc).

Concurrent Session 24: Heart Transplantation: Clinical Issues I

• The Efflcacy Of Oral Steroid Pulse For The Treatment Of Asymptomatic Moderate Cardiac Allograft Rejection.
• The Meaning Of Mild Rejection During Corticosteroid Weaning In Heart Transplant Recipients
• Intention To Transplant Survival. Is This A More Ccurate Predictor Of The Survival Probabilities Of Patients After They Are Accepted For Cardiac Transplantation?
• Hepatitis C Registry Report Intermediate Follow-Up After Cardiac Transplantation
• Combined Heart And Kidney Transplantation Using A Single Donor
• Impact Of Gender Mismatch On The Outcome Of Cardiac Transplantation
• Risk Factors For Malignancies In Heart Transplants Recipients
• Increased Morbidity In Insulin-Dependent Diabetic Patients Long-Term After Heart Transplantation
• Heart Transplantation In The Older Recipient: Initial Results Of A Single Center Experience
• Long Term Mortality And Morbidity With The Use Of Older Donors In Cardiac Transplantation: A Single Center Experience
• Immediate Post-Transplant Myocyte Necrosis Detected By Elevated Serum Levels Of Troponin I Is Associated With An Adverse Long Term Graft Outcome
• Rejection Pattern Of Simultaneously Transplanted Cardiac And Skeletal Muscle In A Rat Model

Concurrent Session 25: Liver Transplantation: Hepatitis and Viral Infections

• Pre-Emptive Treatment With Intravenous Ganciclovir And Serial Pcr Monitoring For Ebv Reduces The Risk Of Lpd In Pediatric Liver Transplant Recipients
• Increased Hepatitis C Viremia In Cholestatic Hepatitis C Following Orthotopic Liver Transplantation. Is The Pathogenecity Of The Syndrome Related To Viral Cytopathic Mechanisms?
• Hepatitis C Infection In Patients Undergoing Hepatic Retransplantion (Retx).
• Quantitation Of Hepatitis C Virus Rna In Liver Tissue Of Allografts: Correlation With Histologic Features And Liver Function Tests.
• Outcomes Comparison Of Patients Undergoing Liver Transplantation For Hepatitis B And Hepatitis C
• Cytomegelovirous Infectian In Liver Trausplant Recipients; Detectian Af Early Antigenemia (Pp65) In Peripheral Blood Leukocytes And Preemptive Therapy.
• Cmv Genotypic Variability Affects Rate Of Rejection But Not Survival After Liver Transplantation.
• Tumor Necrosis Factor (Tnf) Genetic Polymorphisms Correlate With Infections After Liver Transplantation

Concurrent Session 26: Kidney Transplantation: CSA, MMF and Bone Marrow Infusion

• Low-Dose Cyclosporine And Mycophenolate Mofetil In Renal Allograft Recipients With Suboptimal Renal Function
• A Randomised Study Of Conventional Vs Low Dose Cyclosporine In Renal Transplant Recipients Treated With Cyclosporine, Mycophenolate Mofetil And Prednisone.
• Transplantation Without Maintenance Corticosteroids In L-Haplotype And 2.Haplotype Matched Living Related Renal Transplant Recipients Treated With Mycophenolate Mofetil And Cyclosporine
• A Randomized, Double-Blind, Multi-Center Trial Comparing Two Corticosteroid Regimens In Combination With Mycophenolate Mofetil (Mmf) And Cyclosporine (Cya) In Renal Transplant Recipients
• Conversion Of Cyclosporlne (Neoral®; Csa) To Mycophenolate Mofetil (Cellcept®; Mmf) In Stable Renal Transplant Patients
• Donor Bone Marrow, Chimerism, And Kidney Trans Plantation.

Concurrent Session 27: Kidney Transplantation: Donor Issues

• Transplantation Of Pediatric Enbloc Cadaver Kidneys Into Adult Recipients
• Are Two Kidneys Better Than One? Outcome In Single (Sngl) Vs En Bloc (Eb) And Dual (Du) Kidney Transplants (Txp)
• Excellent Kidney Transplant Outcome Using Non-Heart Beating Donor Kidneys
• The Fate Of 359 Renal Allografts Harvested From Non-Heart Beating Uncontrolled Cadavers At A Single Center
• Open Versus Laproscopic Donor Nephrectomy: Is There Adifference In Recipient Renal Function?
• Laparoscopic Live Donor Nephrectomy: The Recipient

Concurrent Session 28: Costimulation

• Do Human Endothelial Cells Utilize The Cd28/B7 Pathway To Costimulate Cd4+ T Cell Activation?
• Allogeneic Endothelium Induces B7-2 Expression In Transmigrating Leukocytes.
• The Role Of A4 Integrin/Fibronectin Interactions In Allospeclfic Cytotoxic T Cell Activation And Homing--Initiai Studies In The 2c T-Cell Receptor Transgenic.
• Alloimmune Reactivity. Inhibitory Effects Of Il-17rf:
• Interferon-Gamma (Ifn_) Is Required For Longterm Allograft Survival Induced By Combined Administration Of Donor-Specific Splenocyte Transfusion (Dsst) And Ctla4ig.
• Costimulation Pathways Operative In Host Immune Responses To Allogeneic Hepatocytes.
• Local Vs. Systemic Immune Inhibition Following Transduction Of Liver Allografts With Ctla4ig

Concurrent Session 29: Animal Models

• Differential Effects Of Cd4 And Cd8 Cells On Apoptosis In Small Intestinal Transplantation
• Accelerated Rate Of Acute Rejection Of Renal Allografts From Brain Dead Donors.
• Inhibition Of Human Skin Allograft Rejection By Blockade Of Cd28-B7 And Cd40-Cd154 Costimulation In The Humanized Scid Mouse (Huscid).
• Interleukin-10 Converting Enzyme (Ice) Mediates Renal Ischemic-Reperfusion Injury In Mice.
• The Impact Of Transient Anti-Donor Antibodies In A Rat Lung Transplant Model
• Distinct Sensitization Pathways In Liver Transplant Recipients

Concurrent Session 30: Cytomegalovirus

• Cmv Antigenemia Directed Preemptive Prophylaxis With Oral Ganciclovir For The Prevention Of Cmv Disease In Liver Transplant Recipients: A Prospective, Randomized, Controlled Trial.
• Effect Of Oral Acyclovir Or Gancyclovir After Preemptive Intravenous Gancyclovir Therapy To Prevent Cytomegalovirus Disease In Cytomegalovirus Seropositive Renal And Liver Transplant Recipients Receiving Antilymphocyte Therapy.
• Novel Mechanism Of Cytomegalovirus Inhibition By Leflunomide: Equjvalent Activity Against Ganciclovir/Foscarnet-Sensitive And Resistant Isolates.
• Comparison Of Pre-Emptive Therapy Based On Pcr With Prophylaxis For Prevention Of Cmv Disease Occurrence In High Risk Transplant Patients
• Prevention Of Cytomegalqvirus Infection Pqst- Renal Transplantation (Clinical Practice Guidelines)
• Intraoperative Hypothermia Is An Independent Risk Factor For Cytomegalovirus (Cmv) Infection In Liver Transplant Recipients.
• Cmv Viral Load In Renal Allograft Recipients
• Incidence Of Gastrointestinal Cytomegalovirus In Renal Transplant Recipients With Abdominal Pain On Mycophenolate Mofetil
• The Risk Of Transfusion-Acquired Cytomegalovirus (Cmv) Infection In Seronegative Solid Organ Transplant Recipients Receiving Unscreened Blood Products (1984. 1996).

Concurrent Session 31: Sensitization and Crossmatching

• Presence Of Cell Microchimerism In Peripheral Blood Of Highly Sensitized Patients Waiting For Renal Transplantation: Possible Mechanism For Long Term Maintenance Of Antibody Titers?
• Can An Immune, Non-Reactive (Anti-Hla) Recipient Be Transplanted Without A Donor-Specific Crossmatch?
• Efficacy And Clinical Relevance Of Elisa-Based Crossmatching (Xm) Relative To The Complement-Dependent Cytotoxicity (Cdc) Xm
• Re-Evaluation Of The Correlation Between Pra-Stat® Reactivity And Renal Allograft Outcome In Light Of Extensive Redefinition Of The Hla Antigen Panel
• Post-Transplant Flow Cytometry Crossmatch And Acute Rejection In Renal Transplantation
• Long-Term Improvement Of Graft Survival In Cadaveric Renal Retransplantation By Flow Cytometric Crossmatching
• Impact Of Race, Transfusions And Pregnancy On Renal Allograft Outcome In Female Recipients
• Allospecific Ifn-_-Producing Cells In Peripheral Blood As A Functional Measure Of Hla Haplotype Match.
• Metalloproteinase Generates Soluble Mhc Class I By Cell Surface Cleavage

Poster Session II: Xenotransplantation

• Cloning Of The Porcine Costimulatory Molecule Cd40.
• Protective Genes In Xenografts Can Be Induced Without T Cells Or Xenoreactive Antibodies.
• Rodent Testis Is Not An Immune Privileged Transplantable Tissue
• Adhesion Molecules Regulating Human Leukocyte Attachment To Porcine Vascular Endothelium
• Xenogeneic Thymic Transplantation In A Pig-To-Non- Human-Primate Model
• Hamster Blood Transfusion Can Induce Tolerance To Cardiac Xenografts In Absence Of T-Cells
• Sustained Decrease Of Serum Anti-Gal Igg Antibodies In Baboons By Removing Aerobic Gram Negative Bacteria From The Bowel And With Cyclophosphamide Treatment.
• Characteristics Of B Lymphocyte And Nk Cell Tolerance In A Hamster-To-Athymic Nude Rat Cardiac Xenotransplantation Model
• Porcine Endogenous Retroviruses And The Safety Of Xenotransplantation
• Analysis Of Public And Private T Cell Repertoire (Tcr) In A Concordant Hamster To Rat Cardiac Xenograft Model.
• In-Vivo In-Vitro.Correlates Of Xenograft Tolerance In Long-Surviving Functional Tolerance (Lsft) Of Cardiac Xenografts (Cx)
• Operational Tolerance (Ot) Of Long-Surviving Cardiac Xenografts (Lscx) Is Related To Modification Of The Graft-In- Residence And Not To Induced Tolerance In The Recipient. Studies Of Retransplanted Lscx
• Cytokine Production From Non-Parenchymal Cells In Isolated Xenoperfused Rat Liver
• Induction Of Species-Specific Host Accommodation In The Hamster-To-Lewis Rat Transplantation Model
• Collagenase Digestion Of The Pig Pancreas Modifies The Expression Of Gal_L-3gal, P^k And Thomsen- Friedenreich Antigens On Adult Porcine Islets
• A New Model For The Study Of Vascular Hyperacute Rejection In Xenotransplantation.
• Characterization Of Xenograft Resistance To Autoimmune Disease Recurrance (Adr) After Pancreas Islet (Pi) Transplants
• Certain Subtypes Of Complement-Fixing Xenoreactive Antibodies Are A Major Factor In Xenograft Rejection.
• Investigation Of Hemolysis Associated With Long. Term Perfusion Of Hdaf And Normal Porcine Livers With Human Blood.
• Anti-Forssman Antibodies In The Rat-Anti-Mouse Sera Are Not Responsible For Rejection Of Mouse Cardiac Xenografts In Rats
• A New Small Animal Model Demonstrates That T-Lymphocytes Are Essential For Rejection Of Vascularized Cardiac Concordant Xenografts
• Human Anti Porcine Xenogeneic T Cell Response In Vitro: Study Of Mixed Leucocyte Reactions And Mixed Lymphoendothelial Cultures
• Tacrolimus Prevents Islet Xenograft Rejection: A Study In The Pig-To-Rat Model
• Rapid Destruction Of Porcine Islets Of Lancerhans By Fresh Human Blood.

Poster Session II: Tolerance

• The Role Of Early Immune Activation And Leucocyte Apoptosis In Induction Of Spontaneous Liver Transplant Tolerance.
• Transferable Allograft Tolerance Induced By Anti-Lfa-1 (Cd11a) Therapy
• Nonresponsiveness To Cardiac Allogbafts Induced By Intrathymic Injection Of Class I Allopeptides Is Associated With Local And Systemic Expression Of Th2 Cytokines
• Cells From Total Lymphoid Irradiated Mice Inhibit Differentiation Of Antigen Specific Th1 Cd4+ Cells
• Characterization Of Novel Surface Molecules On The Facilitating Cell.
• Neonatal Tolerance Is Dependent Upon Thymic Mechanisms
• Allogeneic Liver-Derived Dendritic Cell Progenitors Fail To Stimujlate Intracellular Thi Cytokine Production And Induce Only Low Levels Of Anti-Donor Ctl: Association With `Spontaneous' Liver Allograft Acceptance.
• Transient Enrichment Of Il-4 Producing Cd4-T Nk Cells During The Induction Phase Of Tolerance Following Total Lymphoid Irradiation
• Both Hepatocytes And Liver Non-Parenchymal Cells Are Inducers Of Apoptosis In Activated T Cells
• Combined Simultaneous Blockade Of Cd28/B7 And Cd40/Cd40l Costimulatory Pathways Results In Long-Term Acceptance Of Pancreatic Islet Allografts
• Immune Modulation In Organ Recipients By Single Or Multiple Donor Bone Marrow Infusions
• A Partial Conditioning Model To Achieve Hematopoietic Stem Cell (Hsc) Chimerism In Mice With Type 1 Diabetes
• Tcfp Regulates Cell-Mediated Immunity In Long-Term Allograft Recipients
• Tolerance Induction In Rats Does Not Require Graft Resident Donor-Type Antigen Presenting Cells
• Induction Of Donor Specific Acquired Thymic Tolerance By Intrathymic Inoculation Of A Single Synthetic Allo-Mhc Class 1 Peptide [Rti .A^u]
• Intrathymic Administration Of B Cells Induces Prolonged Survival Of Fully Allogeneic Cardiac Grafts By Non-Deletional Mechanisms
• A Role Of^cd8+T-Cells In The Induction Of Allograft Tolerance By Donor-Specific Blood Transfusion.
• The Induction Of Regulatory T Cells In The Infectious Tolerance Pathway In Allograft Recipients Is Thymus Dependent.
• Donor Specific Hypo-Responsiveness May Not Be Stable In Human Liver Allograpt Recipients Predicted Tolerant By In Vitro T-Cell Function Assays. Background And Methods
• Adult Vascularized Thymus Transplantation Restores Host Immunocompetence
• Immune Privilege Of Liver Allografts Is Regulated By Fas-L (Cd95l)
• Distinct Tolerance Pathways In Sensitized Graft Recipients

Poster Session II: Experimental Immunosuppression

• Failure Of Fibronectin Expression By Graft Infiltrating Macrophages Is Associated With The Infectious Tolerance Pathway In Cd4 Mab-Treated Rat Recipients
• An Active Regulatory Mechanism Of Allograft Tolerance Induced By Cd45rb Monoclonal Antibody (Mab)
• Synergy Of Class I And Class II Mhc Deficiency (C1d And C2d) Islets And Early Short Term Suppression In Achieving Long Term Islet Graft (Ig) Survival And Tolerance Induction
• Involvement Of Cd26/Dpp IV In Alloantigen-Induced Humoral Immune Responses In Allograft Recipients
• Divergent Effects Of Conventional Immunosuppression Agents On Gene Therapy In Transplantation
• Prolongation Of Murine Cardiac And Skin Allograft Survival By Anti-Cd40 Monoclonal Antibody
• Combined Use Of Tacrolimus (Fk506) And Leflunomide (Lef) Results In Prolongation Of Pancreatic Islet Allograft Survival
• Pravastatin-Induced Survival In Rat Orthotopic Liver Transplantation Is Accompanied By Diminished Expression Of B2-Glycoprotein-1 And Proinflammatory Cytokines
• Effect Of Anti-Lfa-1 Monoclonal Antibody On Post- Ischemic Injury In Isolated Kidney Reperfusion
• Nondepleting Anti-Cd4 Antibody Prolongs Adeno-Virus-Mediated Transgene Expression In Syngeneic Heart Transplants.
• Immunomodulatory Function Of Low Molecular Weight Hyaluronate Delays Allograft Re.Iection And Improves Survival In A Rat Acute Kidney Rejection Model.
• Coadministration Of Neoral And The Novel Rapamycin Analog, Sdzrad, To Lung Allograft Recipients: Potentiation Of Immunosuppressive Efficacy And Reduction Of Toxicity By Staggered Vs.Simultaneous Treatment
• Allotrap Peptide Mediated Heme Oxygenase - I Modulation And Immunosuppression
• Effect Of Tacrolimus (Fk506) And Sirolimus (Rapa) Mono- And Combination-Therapy In Prolongation Of Renal Graft Survival In The Monkey
• Low-Dose Oral Sirolimus Prolongs Survival After Orthotopic Liver Transplantation In A Porcine Model.
• Coadministration Of Microemulsion Cyclosporine And The Novel Lefluinomide Malononitrilamide Analog, Hr.1279, More Effectively Suppresses Rat Lung Allograft Rejection Than Microemulsion Cyclosporine Plus Leflunomide
• Geldanamycin Disrupts The P56lck-Heat Shock Protein-90 Complex In T-Cells.
• Prolonged Survival Of Rat Liver Allografts Transfected With Fas-Ligand Expressing Plasmid
• Tamoxifen Prolongs Heart Allograft Survival In Cyclosporin Treated Female Mice
• Flow Cytometric (Fcm) Analysis Of The Molecular
• Mechanisms Of Immunosuppressive Action Of The Active Metabolite Of Leflunomide And Its Malononitrilamide (Mna) Analogs In A Novel Whole Blood Assay
• Inhibition Of Nitric Oxide Synthase Isoforms By Mmunosuppressive Peptides
• Alterations In T Cell Effector Mechanisms Following Transferrin Receptor Blockade
• Tgf-B Mimics And Anti-Tgf-B Reverses The Anti- Proliferative Effects Of Cyclosporine In Vivo
• Temporal Relation Of Immunoregulatory (Suppressor) Cell Function And Skin Graft Survival In Mice Treated With Sirolimus (Sir), Antilymphocyte Sf.Rum (Als) And Donor Specific Bone Marrow (Bm).

Poster Session II: Pancreas and Kidney-Pancreas

• Preliminary Experience With Troglitazone (Rezulin) In Kidney And Kidney/Pancreas Transplant Recipients
• Tacrolimus Use In Kidney-Pancreas Recipients Is Associated With Less Acute Renal Dysfunction Than Cyclosporine
• Outpatient Renal Transplant Biopsies With A Three Hour Observation Period: A Single Center Experience.
• Long-Term Outcome In Simultaneous Kidney And Pancreas (Skp) Transplant Recipients With Functioning Allografts At One Year After Transplantation
• Effects Of Prophilactic Antithymocytic Globu Lins (Atg) On Kidney Rejection Rate In Patients Undergoing Kidney-Pancreas Transplantation:
• Chronic Rejection In Pancreas Transplantation: Risk Factors And The Contribution To Graft Loss
• Correlation Of Histologic Grades Of Pancreas Allograft Rejection To Serum Enzymes And Blood Glucose.
• Chronic Pancreas Allograft Rejection: Morphological Findings And Clinical Correlation
• Incidence And Management Of Mycophenolate Mofetil Adverse Effects In Simultaneous Kidney Pancreas Transplant Recipients
• Efficacy Of Oral Ganciclovir Vs. Oral Acyclovir For Cmv Prophylaxis In Kidney/Pancreas And Pancreas Alone Recipients
• Okt3 As Primary Therapy For Biopsy Proven Acute Renal Allograft Rejection In Simultaneous Kidney And Pancreas Transplant (Skp) Recipients
• Evaluation Of The Arterial Flow Of The Pancreatic Graft With Duplex-Doppler Ultrasonography
• Experience With Azathioprine Withdrawal After Simultaneous Kidney-Pancreas Transplantation

Poster Session II: Pediatrics

• Differences In Recurrent Genetic Anomalies In Ebv-Associated Pediatric Cancer: Use Of Microdissected Archival Material
• Treatment Of Subclinical Acuterejection (Sar) Improves Long-Term Graft Survival By Preventing Late Acute Rejection In Pediatric Renal Transplant Recipients
• Effect Of Mycophenolate Mofetil (Mmf) On Cd4+/Cd8+ Ratio In Pediatric Renal Transplantation (Tx)
• Five Years Post Transplant Status In 96 Children Who Received Olt Between 1984 And 1990.
• Survival After Acute Graft Failure In Pediatric Thoraclc Organ Transplant Recipients.
• Hyperbaric Oxygen Therapy For Hepatic Artery Thrombosis Following Pediatric Liver Transplantation
• Kidney Transplantation In Children Under 5 Years Of Age
• Rejection Incidences After Pediatric Liver Transplantation With Cadaveric Or Living-Related Donors: An Immunological Paradox?
• Use of Mycophenolate in Pediatric Liver Transplantation
• Prevalence And Risk Factors For Anemia In Pediatric Renal Transplant (RTX) Recipients

Poster Session II: Kidney Clinical Trials and Outcomes

• Structure And Function Of High Risk Donor Kidneys Correlate With Recipient Graft Outcome
• Long-Term Graft Survival In Living Kidney Transplantation From Elderly Donors
• Renal Transplantation in Patients with Prior Thoracic Organ Transplants
• Racial Differences In Living Donor Kidney Transplantation

Poster Session II: Delayed Kidney Grade Functions

• Increased Levels Of Alpha-2, 6-Sialyltransferase Pre- Transplant Predict Delayed Graft Function In Kidney Transplants.
• Duration Of Delayed Graft Function Predicts Long Term Graft Survival Need For Dialysis Is Not An Optimal Criterium

Poster Session II: Infectious Complications

• A Comparative Study Of 500 Mc Bid And 250 Mg Bid Of Prophylactic Oral Gancilovir In Post-Kidney Transplant "Cmv At Risk" Recipients
• The Impact Of Mycophenolate Mofetil (Mmf) On Cytomegalowrus (Cmv) Disease.
• Quantitation Of Cmv Viral Infection In Adult Renal Transplant Recipients Utilizing Quantitative Pcr And The Lmv Antgenemia Test
• Prophylaxis Of Viral And Fungal Infections After Simultaneous Kidney-Pancreas Transplantation
• Clinical Course Of Cytomegalovirus (Cmv) Viremia With And Without Ganciclovir Treatment In Cmv- Seropositive Renal Transplant Recipients: Longitudinal Study Of Cmv Pp65 Antigenemia Assay
• Post Kidney Transplant Cmv Incidence In The Gancyclovir Era: Monitoring Viral Dna By A Cmv Pcr Assay
• Transplantation Suppresses Leukocytosis But Not Fever In Patients With Bacterial Or Fungal Infectlon
• Is Azathioprine Harmful To Chronic Viral Hepatitis In Renal Transplantation? A Long-Term Follow-Up Study On Azathioprine Withdrawal.
• Efficacy And Tolerance Of Alpha Interferon Treatment In Dialysis Patients With Chronic Hepatitts C Virus (Hcv): Results Of A Prospective Pilot Study
• Ganciclovir Prophylaxis Is More Effective Than Intravenous Immunoglobulin (Ivig) In Preventing Cytomegalovirus (Cmv)) Disease In Renal Transplant Recipients
• Clostridium Difficile Colitis After Renal Transplantation
• Helicobacter Pylori - Is It Important In The Multi- Organ Transplant Population?
• Acute Renal Allograft Dysfunction And Polyoma Virus Infection: Acute Tubular Necrosis-Like Changes In Absence Of Acute Rejection
• Procalcitonin (Pct) A New Marker For Differential Diagnosis Of Acute Rejection (Ar) And Bacterial Infection (Bi) Heart Transplantation.
• Development Of An Immunosuppressed, Catheterized Murine Model For Ascending Candida Albicans Urinary Tract Infection
• Chagas'disease In Kidney Transplant Patients

Poster Session II: Intrathoracic Organ

• Fk506 Is A Safe And Effective Treatment For Moderate Rejection In Heart Transplant Recipients
• Changes In Homocysteine Concentration After Orthotopic Heart Transplantation
• Detection Of Biopsy Negative Hemodynamicallly Significant Heart Transplant Rejection By Doppler Tissue Imaging
• Are Biochemical Indices Of Acute Cardiac Injury Useful A' Predicting Cardiac Allograft Rejection?
• Quilty B Lesions On Endomyocardial Biopsies: Are They Associated With Subsequent Histologic Rejection In Cardiac Transplant Patients?
• Delayed Acute Allograft Rejection 0ccuring In Patients Who Survive The First Year Post Heart Transplant
• Short Term Use Of Induction Okt3 In Urgent Heart Transplantation: Impact On Long Term Clinical Outcomes
• Long Term Follow-Up Of Heart Transplant Recipients Treated For Acute Allograft Rejection With Methotrexate And/Or Okt3
• Outpatient Okt3 For Cardiac Allograft Rejection - Is It Safe And Cost Effective?
• The Tnf-_ System Before And After Heart Transplantation: Plasma Protein Levels, Mrna-Expression, Soluble Receptors And Serum Buffer Capacity
• Detection Of Coronary Calcification By Electron Beam Computed Tomography In Cardiac Transplant Recipients
• Safety And Tolerability Of Two Different Single Doses Of Sdz Rad In Lung Transplant Recipients
• Neoral Dose Monitoring With 2 Hour Post-Dose Levels In Heart Transplant Patients Receiving Antithymocyte Globulin Induction: A Pilot Study
• Comparison Of Microemulsion Formulation With Oil Based Cyclosporine In Cardiac Transplant Patients
• Intensive Care Unit Outcomes Of Lung Recipients Beyond The Peritransplant Period
• A Randomized Controlled Comparison Of The Efficacy And Safety Of Pravastatin And Simvastatin In Heart Transplantation
• A Safe Strategy For Postoperative Treatment, In Heart Transplant Reciplents Between 60 - 70 Years Of Age
• At What Creatinine Level Is Angiographic Dye Safe For Coronary Angiography In Cardiac Transplant Recipients?
• Association Between Perioperative Renal Function And Time To Chronic Renal Insufficiency Following Orthotopic Heart Transplantation
• The Effect Of Ischemic Time On Rejection And Survival In Cardiac Transplant Recipients
• Treatment Of Atrial Flutter In Cardiac Transplant Recipients
• Four Year Series Of Patients With Lvad-Related Infections: Clinical And Microbiologic Experience With Cardiac Transplantation
• Cardiowest Total Artificial Heart As Successful Bridge To Heart Transplantation In Terminally Ill Heart Failure Patients
• One Year Followup Of Patients Bridged To Heat Transplantation With Jarvik 7 And Cardiowest Total Artificial Heart

Poster II: Bone Marrow

• Ex-Vivo Generation Of Facilitating Cells
• Modulation Of Heme Oxygenase (Hsp-32) By Coralt- Protoporphyrin Abrogates Development Of Acute Gvhd In A Parent To Fl Mouse Model
• Cdr' Cells In The Peripheral Blood Of Mice Treated With G-Csf Enhance The Engraftment Of Purified Hematopoietic Stem Cells Across Allogeneic Barriers
• Mixed Multilineage Chimerism Tn Cd8-Knockout Mice Following Allogeneic Bone Marrow Transplantation With Partial Conditioning
• Influence Of Additional Administration Of Host-Type Bone Marrow On The Immune Tolerance Of Mixed Allogeneic Chimeras

Plenary III

• Impaired Activation-Induced T Cell Apoptosis And Failure To Induce Longterm Allograft Survival In Interleukin-2 (Ii-2) Deficient Mice.
• Hicher Pretransplant Hcv Rna Levels Associated With Poor Patient And Graft Survival
• Thl Responses Control Development Of Graft Vasculopathy: Insights From Studies In Stat4-Knock Out Mice
• A Study Comparing Mycophenolate Mofetil (Mmf) To Azathioprine (Aza) In Simultaneous Pancreas-Kidney (Spk) Transplantation
• Activation Of Cd40 On Human Hepatocytes Increases Fas Ligand Expression And Induces Apoptosis: A Novel Mechanism Of Hepatocyte Loss In Liver Allograft Rejection:
• Recurrent And De Novo Diseases After Renal Traniisplantation, A Report From The Renal Allograft Disease Registru (RADR)
• Are Professional Antigen Presenting Cells (APCS) Necessary To Initiate Graft Rejection?
• Indirect Allorecognition Of Donor Class II MHC Peptides Induces Antibody Mediated Vascular Rejection Of Cardiac Allografts
• Effect Of HLA-DR And Class I CREG Matching Cardiac Transplants (TNX): An Analysis Of Access And utcome
• The Cost-Effectiveness Of Transplantation With Expanded Donor Kidneys (EDKS)- A Markov Model

Concurrent Session 32: Kidney Transplantation: Recurrence, Hypertension, Compliance and High Risk Patients

• Prolonged Hypertension (>10 Years) Is A Significant Risk Factor In Older Cadaver Donor Renal Transplants
• Immunoglobulins are directly involved in the pathogenesis of idiopathic nephrotic syndrome recurrence after renal transplantation
• Odds Probability Of Compliance And Non-Compliance In Patients With A Functioning Renal Transplant- A Multi Center Study
• FK506 Modifies Risk Factors For Chronic Allograft Injury In African-American Renal Allograft Recipients
• The Course And Management Of Hepatitis Band C In Twenty-Year Renal Allograft Recipients (Level 5a)
• Renal Transplantation For ESRD Following Bone Marrow Transplantation: A Report Of 5 Cases With And Without Immunosuppression

Concurrent Session 33: Kidney Transplantation Sirolimus andTacrolimus Immunosuppression

• One-Year Outcome After Steroid Withdrawal From A Sirolimus-Cyclosporine-Prednisone Regimen In Cadaver- And Living-Donor Recipients
• Early Corticosteroid Withdrawal 1 Week Following Renal Transplantation Using Tacrolimus (TAC)/ Mycophenolate Mofetil (MMF) Based Immijnosuppression
• Tacrolimus And Retransplantation: Equivalent Results To Primary Renal Transplantation
• Alopecia Totalis Related To Tacrolimus Use Following Kidney And Pancreas Transplantation
• Randomized Comparative Trial Of Prograf (Tacrolimus) In Combination With Azathioprine Or Mycophenolate Mofetil Vs. Neoral (Cyclosporine) With Mycophenolate Mofetil After Kidney Transplantation
• Cardiovascular Risk Factors In Renal Transplant Recipients: 2-3 Year Results From The FK506 Multicenter, Randomized Comparative Trial

Concurrent Session 34: Tolerance II

• The Role Of CTLA4 Negative Signaling Pathway In The Induction Of Acquired Thymic Tolerance In Vivo
• IL-2 Dependent Rapamycin Resistent Signals Are Required For Tolerance Induction And T Cell Apoptosis
• Attenuation Of IL-2 Receptor Signaling By CD4-Ligation - Molecular Mechanisms
• Alloantigen-Unresponsiveness Is Associated With Early TCR Signaling Defects In Vivo
• Alloantigen-Unresponsiveness Is Associated With Early TCR Signaling Defects In Vivo
• CD4 Cells Maintain CD8 T Cell Anergy In Neonatal Tolerant Mice
• Anti-TCR DNA Vaccination Prolongs Heart Allograft Survival In Adult Rats
• Anti-TCR DNA Vaccination Demonstrates A Role For A CD8+ Clone In Allograft Tolerance Induction
• IL4KO Mice Fail To Develop Long-Term Allograft Survival
• Infectious Tolerance In Renal Allografts: Th2 Cytokines And Induction Of "Protective" Genes Which Inhibit NF-KB Activation
• Tolerance-mediating T cells in renal allografts from anti-CD4 induced tolerant rats express IL-4 and are protected to activation-induced apoptosis (AIA) by upregulation of BAG-l gene

Concurrent Session 35: Experimental Immunosuppression II

• Induction Of The Cycllne Inhibltor P21 Expression By Cyclosporine: A Possible Mechanism For Its Antiproliferative Effects
• Extraction And Quantification Of Cyclosporine From Whole Blood Samples Collected With The Cyclostattmcollection Device
• Synergistic Effects Of Mycophenolate Mofetil (MMF) And Sirolimus (Rapamycin, Rapa) In Prevention Of Acute Heart, Pancreas And Kidney Allograft Rejection And In Reversal Of Ongoing Heart Allograft Rejection In The Rat
• In Vivo Echanisms Of Action Of Leflunomide In Allo-Transplantation And Xeno-Transplantation
• Antithrombin III Inhibits Con A-Induced Proliferation Of Rat Spleen Cells By Inhibiting mRNA Expression Of T Cell Growth Factors (IL-2 and _-IFN) And Improves Parameters Of Acute Inflammation In A Highly Histoincompatible Model Of Rat Lung Allograft Rejection (AR)

Concurrent Session 36: Socioeconomic Issues

• Risks And Costs Of Developing End-Stage Renal Disease After Heart Transplantation
• Living Unrelated Kidney Donation: Is Quality Of Life Affected?
• Medication Compliance Following Renal Transplant
• Who Should Be Transplanted With Kidneys From Ideal Donors Versus Marginal Donors ? A Cost-Effectiveness Analysis
• Ethical Issues In Living Related (LR) Or Cadaveric (Cad) Pediatric Liver Transplantation (OLT)
• Significance Of Patient, Sociodemographic, And Insurance Factors On Access To Liver Transplantation

Concurrent Session 37: Immunosuppression and Histocompatibility in Pancreas Transplantation

• Predictors Of Long Term Graft Survival In Simultaneous Pancreas-Kidney Transplants: A Multivariate Analysis Of The Unos Data
• Single Center Experience Of 50 Consecutive Pancreas Transplant Recipients Receiving Mycophenolate Mofetil (Mmf) And Tacrolimus (Tac) As Primary Maintenance Immunotherapy.
• Registry Report On Pancreas Retransplantation: Lower Incidence Of Rejection In The Tacrolimus Era
• Response To Immunosuppressive Treatment For Pancreas Allograft Rejection According To Histologic Grade
• Long-term Follow-up of Mycophenolic Acid Blood Trough Levels in Graft Recipients with and without a History of Insulin-dependent Diabetes Mellitus IDDM
• Simultaneous Kidney-Pancreas Transplantation Without Antilymphocyte Induction
• ATG Induction Versus No ATG Induction Immunosuppession In Simultaneous Pancreas-Kidney (SPK) Transplantation: Results Of A Single Center Randomized Trial
• Benefits And Risks Of Early Anti-Lymphocite Rescue In Simultaneous Kidney-Pancreas Transplant Recipients
• Trends In Immunosuppression After Pancreas Transplantation: Evolution Or Revolution?

Concurrent Session 38: Viral Infections and Lymphoproliferative Disease

• Clinical Features Of Polyoma Virus Interstitial Nephritis In The Allograft Kidney
• Cytotoxicity Of Lak Cells And Ebv-Specific T Cells Against Lymphoblastoid Ebv-Positive B Cells: A Model For Cellular Therapy Of PTLD
• Sequential Therapy of Post Transplant Lymphoproliferative Disorder (PTLD)
• Natural History Of Epstein-Barr Viral Load In Peripheral Blood In Pediatric Liver Transplant Recipients During Treatment For Post-Transplant Lymphoproliferative Disorder (PTLD)

Concurrent Session 39: Kidney Transplantation: Risk Factors

• 5, 10-MTHFR (C677T) Gene Polymorphism and Total Homocysteine Levels in Renal Transplant Recipients
• Posttransplant Improvement In Heart Rate Variability Correlates With Improved Quality Of Life
• Renal Transplantation In Type II Diabetic Patients
• Renal Function After Nephrectomy In The Elderly And Hypertensive: Implications For Living Donors
• In Vitro Testing Of Fsgs Patient's Sera For Glomerular Permeability Activity (PALB)

Concurrent Session 40: Kidney Transplantation: New Immunosuppresions

• Reduced Acute Rejection And Superior One Year Renal Allograft Survival With Basiliximab (Simulecttm) In Patients With Diabetes Mellitus

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